Growth hormone deficiency (GHD), or human growth hormone deficiency, is a medical condition resulting from not enough growth hormone (GH).[3] Generally the most noticeable symptom is that an individual attains a short height.[1] Newborns may also present low blood sugar or a small penis size.[2] In adults there may be decreased muscle mass, high cholesterol levels, or poor bone density.[1]
GHD can be present at birth or develop later in life.[1] Causes may include genetics, trauma, infections, tumors, or radiation therapy.[2] Genes that may be involved include GH1, GHRHR, or BTK.[3] In a third of cases no cause is apparent.[2] The underlying mechanism generally involves problems with the pituitary gland.[2] Some cases are associated with a lack of other pituitary hormones, in which case it is known as combined pituitary hormone deficiency.[4] Diagnosis involves blood tests to measure growth hormone levels.[2]
Treatment is by growth hormone replacement using synthetic human growth hormone.[1] The frequency of the condition is unclear.[2] Most cases are initially noticed in children.[1] The genetic forms of this disease are estimated to affect about 1 in 7,000 people.[3] Most types occur equally in males and females though males are more often diagnosed.[2]
^ abcdefghi"Growth hormone deficiency". Genetic and Rare Diseases Information Center (GARD) – an NCATS Program. 2016. Retrieved 12 December 2017.
^ abcdefghijkl"Growth Hormone Deficiency". NORD (National Organization for Rare Disorders). 2016. Retrieved 12 December 2017.
^ abcd"isolated growth hormone deficiency". Genetics Home Reference. February 2012. Retrieved 12 December 2017.
^"Combined pituitary hormone deficiency". Genetics Home Reference. August 2010. Retrieved 13 December 2017.
and 21 Related for: Growth hormone deficiency information
used as a prescription drug to treat children's growth disorders and adult growthhormonedeficiency. In the United States, it is only available legally...
achondroplasia, a genetic disorder whereby the limbs are diminutive. Growthhormonedeficiency is responsible for most other cases. There are also many other...
gigantism), deficiency, the recent phenomenon of HGH controversies, growthhormone in sports, and growthhormone for cows. Growthhormonedeficiency is treated...
(FSH) and/or luteinizing hormone (LH) leading to sex hormone abnormalities. Growthhormonedeficiency is more common in people with an underlying tumor than...
main clinical application of these agents is the treatment of growthhormonedeficiency. They also see black market use, similarly to anabolic steroids...
several other endocrine disorders. Growthhormonedeficiency. Some children simply don't produce enough growthhormones, including those born with a poorly...
Laron syndrome (LS), also known as growthhormone insensitivity or growthhormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized...
treatment for reduced levels of these hormones, such as in children or elderly adults with growthhormonedeficiency, and human studies have shown it to...
of GrowthHormoneDeficiency in Adults (QoL-AGHDA) is a disease specific patient-reported outcome measure which measures the effect growthhormone deficiency...
assess growth hormone (GH) secretion for the purpose of diagnosing growthhormonedeficiency. It is a 29-amino acid polypeptide representing the 1–29 fragment...
in the growthhormone locus. Mutations in or deletions of the gene lead to growthhormonedeficiency and short stature. Placental growthhormone Somatotropin...
degree, the growthhormone. However, later endogenous hormones mainly have value in the treatment of micropenis caused by hormonedeficiencies, such as hypopituitarism...
affecting children, such as constitutional growth delay, precocious puberty, thyroid dysfunction, growthhormonedeficiency, and other causes of abnormally short...
offenders with paraphilias or hypersexuality Growthhormone therapy for growthhormonedeficiency Thyroid hormone replacement in hypothyroidism Antithyroid...
of human growthhormone (HGH) as treatment method have centered on the claims, products, and businesses related to the use of growthhormone as an anti-aging...
Pharmaceutical in Japan in a single-dose formulation for the assessment of growthhormonedeficiency (GHD). Pralmorelin is an orally-active, synthetic peptide drug...
Indian media. As a child, Rozik was diagnosed with dwarfism, a growthhormonedeficiency which could be cured with appropriate medical treatment. However...
Global Information