Glycylcyclines are a class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms of tetracycline resistance, namely resistance mediated by acquired efflux pumps and/or ribosomal protection. Presently, tigecycline is the only glycylcycline approved for antibiotic use.
Glycylcyclines are a class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms...
antibiotic medication for a number of bacterial infections. It is a glycylcycline class drug that is administered intravenously. It was developed in response...
Children receiving long- or short-term therapy with a tetracycline or glycylcycline may develop permanent brown discoloration of the teeth. Be inactivated...
the first ketolide 2003 – daptomycin 2005 – tigecycline, the first glycylcycline 2005 – doripenem 2009 – telavancin, the first lipoglycopeptide 2010...
limiting tetracycline's effectiveness in treatment of bacterial disease. Glycylcyclines and fluorocyclines are new classes of antibiotics derived from tetracycline...
late 2000s and early 2010s: cyclic lipopeptides (such as daptomycin), glycylcyclines (such as tigecycline), oxazolidinones (such as linezolid), and lipiarmycins...
the bacterial 30S ribosomal subunit. Tetracyclines and Tigecycline (a glycylcycline related to tetracyclines) block the A site on the ribosome, preventing...
"Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines". The Journal of Antimicrobial Chemotherapy. 58 (2): 256–65. doi:10...
fluoresces under UV light. Other drugs derived from tetracycline such as glycylcycline share this side effect.[medical citation needed] Because tetracyclines...
"Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines". Journal of Antimicrobial Chemotherapy. 58 (2): 256–265. doi:10.1093/jac/dkl224...
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