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Global aphasia information


Global aphasia
Global aphasia occurs due to a lesion in the perisylvian cortex, including Broca's and Wernike's areas.[1]

Global aphasia is a severe form of nonfluent aphasia, caused by damage to the left side of the brain, that affects[1] receptive and expressive language skills (needed for both written and oral language) as well as auditory and visual comprehension.[2] Acquired impairments of communicative abilities are present across all language modalities, impacting language production, comprehension, and repetition.[3][1] Patients with global aphasia may be able to verbalize a few short utterances and use non-word neologisms,[4] but their overall production ability is limited.[1] Their ability to repeat words, utterances, or phrases is also affected.[1] Due to the preservation of the right hemisphere, an individual with global aphasia may still be able to express themselves through facial expressions, gestures, and intonation.[3][5][6] This type of aphasia often results from a large lesion of the left perisylvian cortex. The lesion is caused by an occlusion of the left middle cerebral artery[4][7] and is associated with damage to Broca's area, Wernicke's area, and insular regions which are associated with aspects of language.[8][9]

  1. ^ a b c d e Kemmerer, David (2015). Cognitive Neuroscience of Language. New York: Psychology Press. p. 86. ISBN 978-1-84872-621-5.
  2. ^ Brookshire, R. H. (2007). Introduction to neurogenic communication disorders (Seventh edition.). St. Louis, Mo.: Mosby Elsevier.
  3. ^ a b Goodglass, H., and Kaplan, E. (1983). The assessment of aphasia and related disorders. Philadelphia: Lea and Febiger.
  4. ^ a b Manasco, H. M. (2014). Introduction to Neurogenic Communication Disorders. Burlington, MA: Jones & Barlett Learning.
  5. ^ Cite error: The named reference :4 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference :8 was invoked but never defined (see the help page).
  7. ^ Alexander, M.P. & Loverso, Felice. (1992). A specific treatment for global aphasia. Clinical Aphasiology, 21.
  8. ^ Ozeren, A., Koc, F., Demirkiran, M., Sönmezler, A., & Kibar, M. (2006). Global aphasia due to left thalamic hemorrhage. Neurology India, 54(4), 415-417.
  9. ^ Yourganov, G.; Smith, K. G.; Fridriksson, J.; Rorden, C. (2015). "Predicting aphasia type from brain damage measured with structural MRI". Cortex. 73: 203–215. doi:10.1016/j.cortex.2015.09.005. PMC 4689665. PMID 26465238.

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