Genmab A/S is a Danish biotechnology company, founded in February 1999 by Florian Schönharting, at the time managing director of BankInvest Biomedical venture fund.[7] The company is based in Copenhagen, Denmark – internationally, it operates through the subsidiaries Genmab B.V. in Utrecht, The Netherlands, Genmab U.S., Inc. in Princeton, USA, and Genmab K.K. in Tokyo, Japan. Genmab is a dual-listed company with shares traded on both the Copenhagen Stock Exchange in Denmark[8] and the NASDAQ Global Select Market in the US.[9]
The company has 8 approved antibodies (monoclonal and bispecific) used in 8 marketed products, covering cancer indications and autoimmune diseases.[6]
Proprietary, marketed with partners:
Epkinly/Tepkinly (epcoritamab) for the treatment of Relapsed/refractory diffuse large B-cell lymphoma (DLBCL) (AbbVie)
Tivdak (tisotumab vedotin) for the treatment of previously treated recurrent or metastatic cervical cancer (Seagen)
Marketed by partners:
Darzalex (IV) (daratumumab) / Darzalex Faspro (SC) (daratumumab and hyaluronidase) for the treatment of all stages of multiple myeloma as combination therapy or monotherapy, and for the treatment of newly diagnosed amyloid light-chain (AL) amyloidosis (Janssen)
Kesimpta (ofatumumab) for the treatment of relapsing remitting multiple sclerosis (Novartis)
Rybrevant (amivantamab) for the treatment of non-small-cell lung cancer (EGFR exon 20 insertion mutations) (Janssen)
Talvey (talquetamab) for the treatment of relapsed/refractory MM (Janssen)
Tecvayli (teclistamab) for the treatment of relapsed/refractory MM (Janssen)
Tepezza (teprotumumab) for the treatment of thyroid eye disease (Horizon)
Furthermore both Genmab and its partners have a whole range of antibody programs, building on Genmab technologies, in clinical and pre-clinical development in both cancer and autoimmune diseases. Genmab have several late stage clinical programs for tisotumab vedotin (cervical cancer, ovarian cancer and solid tumors) and epcoritamab (B-cell non-Hodgkin lymphoma and Relapsed/refractory Follicular lymphoma). The partners have, among others, clinical programs for daratumumab (non-MM blood cancers), amivantamab (gastric cancer and esophageal cancer), Mim8 (Factor VIII mimetic bi-specific antibody) (Haemophilia A), inclacumab (VOC in Sickle cell disease) and teprotumumab (diffuse cutaneous systemic sclerosis).[citation needed]
^"OMX Copenhagen 25 index info".
^"Biotekstjerne spottede de gode forretninger". Berlingske. Berlingske. Retrieved 14 November 2020.
^"Marketscreener". Marketscrenner. Marketscreener. Retrieved 14 November 2020.
the subsidiaries Genmab B.V. in Utrecht, The Netherlands, Genmab U.S., Inc. in Princeton, USA, and Genmab K.K. in Tokyo, Japan. Genmab is a dual-listed...
cells. Daratumumab was originally developed by Genmab, but it is now being jointly developed by Genmab along with the Johnson & Johnson subsidiary Janssen...
leukemia (CLL) in the United States. It is sold by Novartis under license from Genmab. The most common side effects for ofatumumab (Kesimpta) include upper respiratory...
co-developed with Astellas Pharma, tisotumab vedotin, being co-developed with Genmab, SGN-LIV1A, an ADC targeting LIV-1, and several immuno-oncology agents in...
CD20-directed CD3 T-cell engager. Epcoritamab was co-developed by AbbVie and Genmab. Epcoritamab was approved for medical use in the United States in May 2023...
Trucking DSV 2000 1976 FLSmidth & Co. Construction and engineering FLS 1882 Genmab Biotechnology GMAB 2000 1999 GN Store Nord Health care equipment GN 2000...
epcoritamab, a blood-cancer therapy under development in partnership with Genmab. The name "AbbVie" is derived from a combination of "Abbott", the name of...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
cycle and kills the cell by apoptosis. Tisotumab vedotin was developed by Genmab in Utrecht, the Netherlands, and Copenhagen, Denmark, with the code name...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
following the last dose. It is a human monoclonal antibody developed by Genmab and Roche for tumour treatment but was later researched by River Vision...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
Retrieved 21 May 2021 – via PR Newswire. "Genmab Announces that Janssen has been Granted U.S. FDA" (Press release). Genmab A/S. 21 May 2021. Archived from the...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
(13): 1205–1214. doi:10.2174/1389450115666141029234644. PMID 25355180. "Genmab.com / HuMax-CD20 (ofatumumab)". Archived from the original on 11 September...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
agreements with Boehringer Ingelheim, Sanofi Pasteur, Johnson & Johnson, Genmab, the Bill & Melinda Gates Foundation, Eli Lilly and Company, GlaxoSmithKline...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
original (PDF) on 21 September 2021. Retrieved 21 September 2021. "Seagen and Genmab Announce FDA Accelerated Approval for Tivdak (tisotumab vedotin-tftv) in...
professional. Connelly is Chairman of the Board of the European Biotech company Genmab A/S, member of the Boards of Macy’s Inc. and the Lincoln Financial Group...
companies Denmark Ambu Carlsberg Chr. Hansen Coloplast Danske Bank DSV Genmab GN Store Nord Novo Nordisk Ørsted Vestas Wind Systems Finland Fortum KONE...
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