A GeneRIF or Gene Reference Into Function is a short (255 characters or fewer) statement about the function of a gene. GeneRIFs provide a simple mechanism for allowing scientists to add to the functional annotation of genes described in the Entrez Gene database. In practice, function is constructed quite broadly. For example, there are GeneRIFs that discuss the role of a gene in a disease, GeneRIFs that point the viewer towards a review article about the gene, and GeneRIFs that discuss the structure of a gene. However, the stated intent is for GeneRIFs to be about gene function. Currently over half a million geneRIFs have been created for genes from almost 1000 different species.[1]
GeneRIFs are always associated with specific entries in the Entrez Gene database. Each GeneRIF has a pointer to the PubMed ID (a type of document identifier) of a scientific publication that provides evidence for the statement made by the GeneRIF. GeneRIFs are often extracted directly from the document that is identified by the PubMed ID, very frequently from its title or from its final sentence.
GeneRIFs are usually produced by NCBI indexers, but anyone may submit a GeneRIF.
To be processed, a valid Gene ID must exist for the specific gene, or the Gene staff must have assigned an overall Gene ID to the species. The latter case is implemented via records in Gene with the symbol NEWENTRY. Once the Gene ID is identified, only three types of information are required to complete a submission:
a concise phrase describing a function or functions (less than 255 characters in length, preferably more than a restatement of the title of the paper);
a published paper describing that function, implemented by supplying the PubMed ID of a citation in PubMed;
a valid e-mail address (which will remain confidential).
A GeneRIF or Gene Reference Into Function is a short (255 characters or fewer) statement about the function of a gene. GeneRIFs provide a simple mechanism...
every year; tasks included information retrieval, document classification, GeneRIF prediction, and question answering. TREC, the Text Retrieval Conference...
regulators correlates with inhibition of transcription. One can refer to the GeneRIFs of the SUMO proteins, e.g. human SUMO-1, to find out more. There are 4...
Biopic about Dutch art forger Han van Meegeren Legionnaire 1998 1920–1926 Rif War The First of the Few 1942 1922–1936 Aerospace engineer R.J. Mitchell...
Repeated implantation failure (RIF) is the repeated failure of the embryo to implant onto the side of the uterus wall following IVF treatment. Implantation...
related publication on PubMed PubMed GeneRIFs (summaries of related scientific publications) - [1] Weizmann Institute GeneCard for TCF7L2 Overview of all the...
Peter Del Vecho, Jeff Draheim, Rob Edwards, Eddie Frierson, Bridget Hoffman, Rif Hutton, John Kassir, Mona Marshall, John Musker, Phil Proctor, Peter Renaday...
Bettin, Ian Abercrombie, Bridget Hoffman, Richard Horvitz, Sherry Hursey, Rif Hutton, Steve Bulen, Tony Pope, Peter Renaday, Moosie Drier, Iake Eissinmann...
29%. The fully automated PCR test using the Cepheid GeneXpert system of the Xpert Ultra MTB/RIF has improved sensitivity of up to 77% in persons with...
Mueller-Stahl, Vincent D'Onofrio, Dennis Haysbert, Shiri Appleby, Leon Rippy, Rif Hutton, Janet MacLachlan, Steven Schub, Alison Lohman 29 Inherit the Wind...
first-order logic that is based on S-expressions. Rule Interchange Format (RIF), F-Logic and its successor ObjectLogic combine ontologies and rules. OWL...
Scozzari, R; MacAulay, V; Torroni, A (2003). "Extensive Female-Mediated Gene Flow from Sub-Saharan Africa into Near Eastern Arab Populations". American...
Tommy Hinkley, Patti Yasutake, Majel Barrett, Barbara March, Gwynyth Walsh, Rif Hutton, Brian Thompson, Thomas Alexander Dekker, Olivia Hack, Whoopi Goldberg...
"Doogie" Howser Dr. Jack McGuire Dr. Pinkley Dr. Ron Welch Lawrence Pressman James Sikking Neil Patrick Harris Mitchell Anderson Susan Krebs Rif Hutton...
1969–79 Van Hughes Cole Thornhart 2012 Duncan Hursley Mechanic Bill 2014 Rif Hutton Lenny Caulfield 2021–22 Julio Iglesias Himself 1994 Mele Ihara Reiko...
resistance genes (AMR genes). These genes are transferred via plasmids from and to other human pathogens. One human pathogen that commonly acquires AMR genes from...
"Doogie" Howser Dr. Jack McGuire Dr. Pinkley Dr. Ron Welch Lawrence Pressman James Sikking Neil Patrick Harris Mitchell Anderson Susan Krebs Rif Hutton...
better than other currently available commercial tests." Xpert ® MTB/RIF and Xpert MTB/RIF Ultra has high specificity in diagnosing extrapulmonary tuberculosis...
2015, Hezbollah forces launches a new offensive in the Qalamoun region in Rif DImashq Governorate, supported by the Syrian Army with the aim of clearing...
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