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Gene therapy for color blindness information


Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals with congenital color blindness by introducing typical alleles for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys suggesting an imminent gene therapy in humans. While the research into gene therapy for red-green colorblindness has lagged since then, successful human trials are ongoing for achromatopsia. Congenital color vision deficiency affects upwards of 200 million people in the world, which represents a large demand for this gene therapy.

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Gene therapy for color blindness

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Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals...

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Color blindness

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Color blindness or color vision deficiency (CVD) is the decreased ability to see color or differences in color. The severity of color blindness ranges...

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List of therapies

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therapy gene therapy for color blindness gene therapy for epilepsy gene therapy for osteoarthritis gene therapy in Parkinson's disease gene therapy of the...

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Gene therapy

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current. Gene therapy for color blindness Gene therapy for epilepsy Gene therapy for osteoarthritis Gene therapy in Parkinson's disease Gene therapy of the...

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Therapy

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genes: gene therapy gene therapy for epilepsy gene therapy for osteoarthritis gene therapy for color blindness gene therapy of the human retina gene therapy...

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Stem cell therapy for macular degeneration

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Journal of Medicine. Cell therapy Ophthalmology Stem cell therapy Macular degeneration Gene therapy for color blindness Gene therapy of the human retina Atala...

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Gene therapy of the human retina

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Retinal gene therapy holds a promise in treating different forms of non-inherited and inherited blindness. In 2008, three independent research groups...

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Achromatopsia

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symptom. The conditions include: monochromatic color blindness, poor visual acuity, and day-blindness. The syndrome is also present in an incomplete form...

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Retinitis pigmentosa

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therapy are additional useful tools for those managing progressive visual decline. Retinitis pigmentosa is the leading cause of inherited blindness,...

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Macular degeneration

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Macula of retina Visual impairment Gene therapy for color blindness Gene therapy of the human retina Stem cell therapy for macular degeneration epiretinal...

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Jay Neitz

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color-blindness. Their work on treating color-blindness in monkeys received some attention in the popular science press. In this work, they gave gene...

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Choroideremia

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see [4] and [5] and [6], accessed 23 April 2015. CT.gov, 2014, "Gene Therapy for Blindness Caused by Choroideremia (Sponsor:University of Oxford): NCT01461213...

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Cystic fibrosis

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"Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial"....

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Occult macular dystrophy

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including darkened vision, ring scotoma (ring of blindness close to the center of vision), color blindness, and difficulty with bright lights. The scotoma...

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Dobermann

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32–35 kilograms (71–77 lb). Two different color genes exist in the Dobermann: one for black (B) and one for color dilution (D). There are nine possible combinations...

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Visual impairment

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Bias blind spot). A 2008 study tested the effect of using gene therapy to help restore the sight of patients with a rare form of inherited blindness, known...

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Appaloosa

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the leopard complex (LP) gene are also at risk for congenital stationary night blindness (CSNB). This form of night blindness has been linked with the...

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Genetic disorder

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less serious conditions such as male pattern baldness and red–green color blindness. X-linked recessive conditions can sometimes manifest in females due...

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Sickle cell disease

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is mutated, may be a good candidate for gene therapy treatment. The risks and benefits related to gene therapy for sickle cell disease are not known. In...

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Rhodopsin

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sensitive. Defects in the rhodopsin gene cause eye diseases such as retinitis pigmentosa and congenital stationary night blindness. Rhodopsin was discovered by...

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Stephen Tsang

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studies metabolic signaling in retinal diseases, as well as gene therapy and stem cell therapy to treat such diseases. In 2010, Tsang led an international...

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Stargardt disease

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utilized to ensure a proper diagnosis for which the correct treatment can be applied. At present there is no gene therapy for Stargardt Disease. However, ophthalmologists...

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Retina

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interior of the globe. Night blindness: Night blindness occurs in any person with severe vitamin A deficiency. The reason for this is that without vitamin...

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Gene Tierney

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Gene Eliza Tierney (November 19, 1920 – November 6, 1991) was an American film and stage actress. Acclaimed for her great beauty, she became established...

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Portuguese Water Dog

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retinal atrophy, which causes "night blindness", may lead to complete blindness. This is a simple recessive gene. DNA testing, known as "Optigen Testing"...

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Keeshond

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the characteristic shading of color. The color may vary from light to dark, but any pronounced deviation from the grey color is not permissible. The plume...

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Genetically modified organism

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relevant to human gene therapy. There are proposals to remove the virulent genes from viruses to create vaccines. Plants have been engineered for scientific...

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