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Gelatin microparticle information


Gelatin Microparticles are polymer microparticles constructed of gelatin. Gelatin, a bipolymer, is produced through the hydrolysis of collagen. Gelatin, along with its more familiar uses, is widely used for the production of microparticles due to its efficiency in forming gels as well as its biodegradability as a particle. Gelatin can be manipulated to form a stable matrix for biologically reactive compounds, allowing for the incorporation and protection against enzymatic degradation.[1] Gelatin Microparticles are versatile particles and are easily loadable for the use within drug systems[2] and alongside growth factors post-synthesis.[3] Gelatin microparticles also allow for the biochemically controlled release of drug particles, growth factors, and other biological molecules.[1]

  1. ^ a b Kong; Li; Wang; Adhikari (2011). "Preparation of gelatin microparticles using water-in-water (w/w) emulsification technique". Journal of Food Engineering. 103: 103(1): 9–13. doi:10.1016/j.jfoodeng.2010.09.012.
  2. ^ García Cruz, D. M.; Sardinha, V.; Escobar Ivirico, J. L.; Mano, J. F.; Gómez Ribelles, J. L. (18 November 2012). "Gelatin microparticles aggregates as three-dimensional scaffolding system in cartilage engineering". Journal of Materials Science: Materials in Medicine. 24 (2): 503–513. doi:10.1007/s10856-012-4818-9. hdl:1822/24890. PMID 23160914. S2CID 8823795.
  3. ^ Patel, Z; Yamamato, M; Ueda, H; Tabata, Y; Mikos, A (2008). "Biodegradable Gelatin Microparticles as Delivery Systems for the Controlled Release of Bone Morphogenetic Protein-2". Acta Biomater. 5 (4): 1126–1138. doi:10.1016/j.actbio.2008.04.002. PMC 3018807. PMID 18474452.

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