Ganoderic acid information

Ganoderic acid A
Names
	IUPAC name (25R)-7β,15α-Dihydroxy-3,11,23-trioxolanost-8-en-26-oic acid
	Systematic IUPAC name (2R,6R)-6-[(1R,3S,3aR,4S,5aR,9aS,11aR)-3,4-Dihydroxy-3a,6,6,9a,11a-pentamethyl-7,10-dioxo-2,3,3a,4,5,5a,6,7,8,9,9a,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-methyl-4-oxoheptanoic acid
Identifiers
CAS Number	81907-62-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	413668 ;
PubChem CID	471002;
UNII	548G37DF65 ;
CompTox Dashboard (EPA)	DTXSID80903984 ;
	InChI InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1 Key: DYOKDAQBNHPJFD-JNTBEZBXSA-N ; InChI=1/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1 Key: DYOKDAQBNHPJFD-JNTBEZBXBK;
	SMILES OC(=O)[C@H](C)CC(=O)C[C@@H](C)[C@H]2C[C@H](O)[C@@]1(C)C/3=C(\C(=O)C[C@@]12C)[C@@]4(C)CCC(=O)[C@](C)(C)[C@@H]4C[C@@H]\3O;
Properties
Chemical formula	C30H44O7
Molar mass	516.67
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia.^[1]^[2] Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. The two most well described ganoderic acids out of the many that have been identified and characterized are ganoderic acids A and B. Some ganoderic acids have been found to possess biological activities including hepatoprotection,^[3] anti-tumor effects,^[4] and 5-alpha reductase inhibition.^[5]

^ Nishitoba, Tsuyoshi; Goto, Sanae; Sato, Hiroji; Sakamura, Sadao (1989). "Bitter triterpenoids from the fungus Ganoderma applanatum". Phytochemistry. 28 (1): 193–7. Bibcode:1989PChem..28..193N. doi:10.1016/0031-9422(89)85036-8.
^ Cite error: The named reference Mizuno 1995 was invoked but never defined (see the help page).
^ Liu, Li-Ying; Chen, Hui; Liu, Chao; Wang, Hong-Qing; Kang, Jie; Li, Yan; Chen, Ruo-Yun (2014). "Triterpenoids of Ganoderma theaecolum and their hepatoprotective activities". Fitoterapia. 98: 254–9. doi:10.1016/j.fitote.2014.08.004. PMID 25111010.
^ Cite error: The named reference pmid_17466920 was invoked but never defined (see the help page).
^ Cite error: The named reference pmid_16962782 was invoked but never defined (see the help page).

[Hokkaido_University_2001-1] Nishitoba, Tsuyoshi; Goto, Sanae; Sato, Hiroji; Sakamura, Sadao (1989). "Bitter triterpenoids from the fungus Ganoderma applanatum". Phytochemistry. 28 (1): 193–7. Bibcode:1989PChem..28..193N. doi:10.1016/0031-9422(89)85036-8.

[Mizuno_1995-2] Cite error: The named reference Mizuno 1995 was invoked but never defined (see the help page).

[3] Liu, Li-Ying; Chen, Hui; Liu, Chao; Wang, Hong-Qing; Kang, Jie; Li, Yan; Chen, Ruo-Yun (2014). "Triterpenoids of Ganoderma theaecolum and their hepatoprotective activities". Fitoterapia. 98: 254–9. doi:10.1016/j.fitote.2014.08.004. PMID 25111010.

[pmid_17466920-4] Cite error: The named reference pmid_17466920 was invoked but never defined (see the help page).

[pmid_16962782-5] Cite error: The named reference pmid_16962782 was invoked but never defined (see the help page).

Ganoderic acid information

and 5 Related for: Ganoderic acid information

Ganoderic acid

Ganoderma

Aldose reductase

C30H44O7

Steroidogenesis inhibitor