GPX7 information

GPX7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2P31
Identifiers
Aliases	GPX7, CL683, GPX6, GPx-7, GSHPx-7, NPGPx, glutathione peroxidase 7
External IDs	OMIM: 615784; MGI: 1914555; HomoloGene: 128491; GeneCards: GPX7; OMA:GPX7 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	52,609,051 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	108,264,158 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; cartilage tissue; ; ganglionic eminence; ; periodontal fiber; ; gallbladder; ; granulocyte; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; anterior pituitary; ; left uterine tube;
	Top expressed in
	external naris; ; calvaria; ; dermis; ; intervertebral disc; ; efferent ductule; ; cervical vertebral column; ; external carotid artery; ; fossa; ; endocardial cushion; ; thoracic vertebral column;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; glutathione peroxidase activity; catalase activity; protein binding; peroxidase activity;
Cellular component	extracellular region; endoplasmic reticulum lumen; endoplasmic reticulum;
Biological process	response to oxidative stress; cellular oxidant detoxification; cellular response to oxidative stress;
	Sources:Amigo / QuickGO
Orthologs
	2882
	67305
	ENSG00000116157
	ENSMUSG00000028597
	Q96SL4
	Q99LJ6
	NM_015696
	NM_024198
	NP_056511
	NP_077160
	Wikidata
View/Edit Human	View/Edit Mouse

Glutathione peroxidase 7 is an enzyme that in humans is encoded by the GPX7 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116157 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028597 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH (Oct 2004). "Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells". J Biol Chem. 279 (42): 43522–9. doi:10.1074/jbc.M407141200. PMID 15294905.
^ "Entrez Gene: GPX7 glutathione peroxidase 7".

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