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Frequency following response information


The frequency following response (FFR), also referred to as frequency following potential (FFP) or envelope following response (EFR), is an evoked potential generated by periodic or nearly-periodic auditory stimuli.[1][2] Part of the auditory brainstem response (ABR), the FFR reflects sustained neural activity integrated over a population of neural elements: "the brainstem response...can be divided into transient and sustained portions, namely the onset response and the frequency-following response (FFR)".[3] It is often phase-locked to the individual cycles of the stimulus waveform and/or the envelope of the periodic stimuli.[4] It has not been well studied with respect to its clinical utility, although it can be used as part of a test battery for helping to diagnose auditory neuropathy. This may be in conjunction with, or as a replacement for, otoacoustic emissions.[5]

  1. ^ Burkard, R., Don, M., & Eggermont, J. J. Auditory evoked potentials: Basic principles and clinical application. Philadelphia: Lippincott Williams & Wilkins.
  2. ^ Cite error: The named reference worden was invoked but never defined (see the help page).
  3. ^ Russo, N.; Nicol, T.; Musacchia, G.; Kraus, N. (September 2004). "Brainstem responses to speech syllables". Clinical Neurophysiology. 115 (9): 2021–2030. doi:10.1016/j.clinph.2004.04.003. PMC 2529166. PMID 15294204.
  4. ^ Moushegian, G.; Rupert, A. L. (1973). "Response diversity of neurons in ventral cochlear nucleus of kangaroo rat to low-frequency tones". Journal of Neurophysiology. 33 (3): 351–364. doi:10.1152/jn.1970.33.3.351. PMID 5439342.
  5. ^ Pandya, PK; Krishnan, A (March 2004). "Human frequency-following response correlates of the distortion product at 2F1-F2" (PDF). Journal of the American Academy of Audiology. 15 (3): 184–97. doi:10.3766/jaaa.15.3.2. PMID 15119460.

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