Familial Danish dementia is an extremely rare, neurodegenerative disease characterized by progressive cataracts, loss of hearing, cerebellar ataxia, paranoid psychosis, and dementia. Neuropathological hallmarks include extensive atrophy of all areas of the brain, chronic diffuse encephalopathy, and the presence of exceedingly thin and nearly totally demyelinated cranial nerves.[1]
FDD is an autosomal dominant disorder caused by a mutation in the BRI2 gene on chromosome 13.[4] FDD is one of the two types of hereditary, cerebral amyloid angiopathy, alongside familial British dementia.[5]
^ ab"ADan amyloidosis - About the Disease". rarediseases.info.nih.gov. Retrieved 22 July 2023.
^Paul, Robert H. (2007-11-17). Vascular Dementia: Cerebrovascular Mechanisms and Clinical Management. Springer Science & Business Media. p. 42. ISBN 978-1-59259-824-3.
^Sharma, Pankaj; Meschia, James F. (2012-08-27). Stroke Genetics. Springer Science & Business Media. p. 75. ISBN 978-0-85729-209-4.
^ abcHolton, Janice L.; Lashley, Tammaryn; Ghiso, Jorge; Braendgaard, Hans; Vidal, Ruben; Guerin, Christopher J.; Gibb, Graham; Hanger, Diane P.; Rostagno, Agueda; Anderton, Brian H.; Strand, Catherine (March 2002). "Familial Danish Dementia: A Novel Form of Cerebral Amyloidosis Associated with Deposition of Both Amyloid-Dan and Amyloid-Beta". Journal of Neuropathology & Experimental Neurology. 61 (3): 254–267. doi:10.1093/jnen/61.3.254. ISSN 0022-3069. PMID 11895040.
FamilialDanishdementia is an extremely rare, neurodegenerative disease characterized by progressive cataracts, loss of hearing, cerebellar ataxia, paranoid...
Familial British dementia is a form of dementia. It was first reported by Cecil Charles Worster-Drought in 1933 and is therefore also known as Worster-Drought...
located on chromosome 13. The gene is connected to familialDanishdementia and familial British dementia causing amyloid and pre-filbrillar effects similar...
these diseases are mainly sporadic and only a few cases are familial. Others are only familial. Some result from medical treatment. Prions are an infectious...
in Zambia KAZE-FDD, a political party in Burundi FamilialDanishdementia, a rare form of dementia Floppy disk drive Frequency-division duplex, a telecommunications...
C amyloid (ACys). the "British type" and "Danish type" are associated with British amyloid (ABri) and Danish amyloid (ADan) respectively. Both peptides...
chaperone function. These include BRI2, which is related to familial British and Danishdementia (FBD and FDD); Chondromodulin-I, related to chondrosarcoma;...
fibrillation is independently associated with a higher risk of developing dementia. Among Danish men aged 50, with no risk factors, the 5-year risk of stroke was...
confirmed these findings. MicroRNAs are also proposed to be involved. The dementia that occurs in Down syndrome is due to an excess of amyloid beta peptide...
cause chromosome 3-linked frontotemporal dementia (FTD3), which has been described in several members of one Danish family [1]. In a study of French families...
complete loss of his mental faculties, with paralysis and probably vascular dementia. He lived his remaining years in the care of his mother until her death...
anxiety disorder, etc. Finally, it is a notable characteristic of delirium, dementia, hormonal change, metabolic disturbance, chronic stress, pain, and substance/medication...
study of dementia Mary Broadfoot Walker (born 1888), researched physostigmine in the treatment of myasthenia gravis, and potassium in familial periodic...
gene therapy.[citation needed] In 1961, a Danish ophthalmologist named Mette Warburg reported on a Danish family that showed seven cases of a hereditary...
living and have low social support. For those with adequate social and familial support, home care is delayed until the impairment level becomes severe...
contributor to the progress of unipolar depression, bipolar disorder, dementia, and diabetes. Interventions to improve outcomes include reducing contact...
disorders to help them understand and adapt to the medical, psychological and familial implications of genetic contributions to disease. This field is considered...
sleeping pills may help, they are sometimes associated with injuries, dementia, and addiction. These medications are not recommended for more than four...
sanctuary. Modern definitions portray home as a site of supreme comfort and familial intimacy, operating as a buffer to the greater world. The concept of home...
Institutional abuse can be divided into three categories: Overt abuse – similar to familial abuse in its overt physical, sexual, or emotional abuse by a foster parent...
acids and development of Alzheimer's disease (or several other forms of dementia). The review based this conclusion on finding that 4 of the 5 reports appeared...
somnolence in the elderly. In a trial of valproate in elderly patients with dementia, a significantly higher portion of valproate patients had somnolence compared...
exercised in the light of all factors—physical, emotional, psychological, familial, and the woman's age—relevant to the well-being of the patient. All these...
patient and the quality and length of treatment. A group of adults with dementia participated in group music therapy. In the group, these adults engaged...