Global Information Lookup Global Information

FOXC2 information


FOXC2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFOXC2, FKHL14, LD, MFH-1, MFH1, forkhead box C2
External IDsOMIM: 602402; MGI: 1347481; HomoloGene: 21091; GeneCards: FOXC2; OMA:FOXC2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005251

NM_013519

RefSeq (protein)

NP_005242

NP_038547

Location (UCSC)Chr 16: 86.57 – 86.57 MbChr 8: 121.84 – 121.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1 (MFH1) is a protein that in humans is encoded by the FOXC2 gene.[5][6] FOXC2 is a member of the fork head box (FOX) family of transcription factors.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000176692 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046714 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kaestner KH, Bleckmann SC, Monaghan AP, Schlöndorff J, Mincheva A, Lichter P, Schütz G (June 1996). "Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development". Development. 122 (6): 1751–8. doi:10.1242/dev.122.6.1751. PMID 8674414.
  6. ^ Miura N, Iida K, Kakinuma H, Yang XL, Sugiyama T (May 1997). "Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures". Genomics. 41 (3): 489–92. doi:10.1006/geno.1997.4695. PMID 9169153.

and 19 Related for: FOXC2 information

Request time (Page generated in 0.5702 seconds.)

FOXC2

Last Update:

Forkhead box protein C2 (FOXC2) also known as forkhead-related protein FKHL14 (FKHL14), transcription factor FKH-14, or mesenchyme fork head protein 1...

Word Count : 1624

Meige disease

Last Update:

been linked to a mutations in the ‘forkhead’ family transcription factor (FOXC2) gene located on the long arm of chromosome 16 (16q24.3). It is the most...

Word Count : 177

FOX proteins

Last Update:

Hepatocyte nuclear factors.) FOXB1, FOXB2 FOXC1 (associated with glaucoma), FOXC2 (varicose veins) FOXD1, FOXD2, FOXD3 (vitiligo), FOXD4, FOXD4L1, FOXD4L3...

Word Count : 874

Campomelic dysplasia

Last Update:

STHAG3 3.3 FOXC1 Axenfeld syndrome 3 Iridogoniodysgenesis, dominant type FOXC2 Lymphedema–distichiasis syndrome FOXE1 Bamforth–Lazarus syndrome FOXE3 Anterior...

Word Count : 1003

Chromosome 16

Last Update:

member B FBRS: Probably fibrosin-1 long transcript protein FOXC2-AS1: encoding protein FOXC2 antisense RNA 1 GLG1: Golgi apparatus protein 1 HBAP1: Hemoglobin...

Word Count : 1672

Varicose veins

Last Update:

Ed. Ng MY, Andrew T, Spector TD, Jeffery S (March 2005). "Linkage to the FOXC2 region of chromosome 16 for varicose veins in otherwise healthy, unselected...

Word Count : 4697

BSD domain

Last Update:

promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation". Science Signaling. 6 (257): ra2...

Word Count : 299

List of human transcription factors

Last Update:

ENSG00000054598 Forkhead Known motif – High-throughput in vitro [244] WRWRTMAAYAW FOXC2 ENSG00000176692 Forkhead Known motif – High-throughput in vitro [245] WAHRTMAAYAWW...

Word Count : 81

SYAP1

Last Update:

promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation". Science Signaling. 6 (257): ra2...

Word Count : 408

Tetralogy of Fallot

Last Update:

this gene have been associated with TOF, accounting for 2.4% of all cases. FOXC2 is another gene involved in embryonic development of the cardiac system...

Word Count : 8320

Forkhead box C1

Last Update:

regulation of embryonic and ocular development. FOXC1 and its close relative, FOXC2 are both critical components in the development of the heart and blood vessels...

Word Count : 1796

Cancer stem cell

Last Update:

Hartwell K, Richardson AL, Weinberg RA (June 2007). "Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like...

Word Count : 10288

Tissue nanotransfection

Last Update:

necrotic and decays. Using a patented cocktail of plasmids (Etv2, Fli1, Foxc2, or EFF), these factors were delivered to the tissue above the surgery site...

Word Count : 2013

Developmental bioelectricity

Last Update:

Kanady, J. D; Munger, S. J; Witte, M. H; Simon, A. M (2015). "Combining Foxc2 and Connexin37 deletions in mice leads to severe defects in lymphatic vascular...

Word Count : 17264

List of genes mutated in cutaneous conditions

Last Update:

arachnodactyly Fibulin-4 Fibulin-4 Cutis laxa Fibulin-5 Fibulin-5 Cutis laxa FOXC2 Lymphedema–distichiasis syndrome Meige lymphedema GALNT3 Familial tumoral...

Word Count : 108

GATA2 deficiency

Last Update:

factor contributes to controlling the expression of two genes, PROX1 and FOXC2, which are required for the proper development of the lymphatic system,...

Word Count : 5784

Homeobox protein goosecoid

Last Update:

characteristics. GSC, along with other transcription factors like Twist, FOXC2, and Snail, induce epithelial to mesenchymal transitions by regulating the...

Word Count : 1845

List of OMIM disorder codes

Last Update:

with renal disease and diabetes mellitus; 153400; FOXC2 Lymphedema–distichiasis syndrome; 153400; FOXC2 Lymphoma, non-Hodgkin; 605027; PRF1 Lymphoma, non-Hodgkin...

Word Count : 18877

Margaret Buckingham

Last Update:

Tsutomu; Relaix, Frédéric; Buckingham, Margaret E. (December 2009). "Pax3:Foxc2 Reciprocal Repression in the Somite Modulates Muscular versus Vascular Cell...

Word Count : 1578

PDF Search Engine © AllGlobal.net