The Ewing family of tumors (EFTs) is a group of small cell sarcomas including Ewing sarcoma of the bone, extra osseous Ewing tumors, and primitive neuroectodermal tumors. They are rare cancers, usually diagnosed in peoples' twenties. The sarcoma of bone is the most common of the variants. All forms are predisposed to metastasis and have had historically high rates of mortality. The family of tumors shares a common translocation mutation of the EWS gene on chromosome 22 to an ETS-type gene, most commonly the FLI1 gene.[1] EFTs are highly malignant, with 5-year survival for patients with metastatic disease at 20%. The current standard of care includes resection, radiation, and chemotherapy.[2]
^Iwamoto Y (February 2007). "Diagnosis and treatment of Ewing's sarcoma". Japanese Journal of Clinical Oncology. 37 (2): 79–89. doi:10.1093/jjco/hyl142. PMID 17272319.
^Yu H, Ge Y, Guo L, Huang L (January 2017). "Potential approaches to the treatment of Ewing's sarcoma". Oncotarget. 8 (3): 5523–5539. doi:10.18632/oncotarget.12566. PMC 5354928. PMID 27740934.
and 23 Related for: Ewing family of tumors information
The Ewingfamilyoftumors (EFTs) is a group of small cell sarcomas including Ewing sarcoma of the bone, extra osseous Ewingtumors, and primitive neuroectodermal...
belongs to the Ewingfamilyoftumors. Using gene transfer of SV40 large T-antigen in neuronal precursor cells of rats, a brain tumor model was established...
electrical engineering Emotionally focused therapy, in psychotherapy Ewingfamilyoftumors, in medicine Exploration Flight Test-1, a 2014 NASA test flight...
Extraskeletal Ewing sarcoma (EES), is a cancer of soft tissue, a type ofEwing sarcoma that does not arise from bone. It belongs to the Ewingfamilyoftumors. Typical...
"Evaluation of the Incidence of the Ewing'sFamilyofTumors on Cape Cod, Massachusetts and the PAVE PAWS Radar Station" (PDF). Massachusetts Department of Health...
affect prognosis of bone sarcomas: Size of the tumor: larger tumors tend to have a worse prognosis compared to smaller tumors. Spread oftumor to surrounding...
transcription family gene. These fusion genes are EWSR1-NFATC2, FUS-NFATC2, and EWSR1-PATZ1. Desmoplastic small-round-cell tumors: These tumors' neoplastic...
James Ewing is a fictional character in the American television series Dallas and its 2012 revival. The youngest son of Jock and Miss Ellie Ewing, he was...
and the Ewing'sfamilyoftumors. Malignant ectomesenchymomas may form in the head and neck, abdomen, perineum, scrotum, or limbs. The tumor is defined...
Ewing in the 1978–1991 primetime television soap opera Dallas, and the befuddled astronaut Major Anthony Nelson in the 1965–1970 sitcom I Dream of Jeannie...
Richard Ewing Powell (November 14, 1904 – January 2, 1963) was an American actor, singer, musician, producer, director, and studio head. Though he came...
(1995). "EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive neuroectodermal tumor". Int J Cancer. 63 (4): 500–4. doi:10.1002/ijc.2910630407...
an early form of immunotherapy to eradicate tumors. Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in the summer of 1896 before founding...
there until it ended its run. Gary Ewing (Ted Shackelford) was the middle son and black sheep of the Ewingfamily from Dallas. His father Jock (Jim Davis)...
cisplatin) in adult patients with recurrent or refractory Ewing sarcoma familyoftumors". American Journal of Clinical Oncology. 27 (5): 529–34. doi:10.1097/01...
the family genealogy, however, Zeng had a great-granduncle who was recorded at 233 cm (7 ft 7 in) in height. The cause of Zeng's gigantism was a tumor that...
parts of the body. Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other parts of the...
Ewing High School. She received a B.A. from Thomas Edison State College in 1985 after briefly attending Rutgers University-Camden. She is a member of...
Quality of Life improves with time since diagnosis, especially for children with solid tumors and hematological malignancies. Children with a CNS tumors, on...
site of the primary tumor. Genitourinary tumors may present with hematuria, urinary tract obstruction, and/or a scrotal or vaginal mass. Tumors that arise...
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