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Eryptosis information


Eryptosis (Erythrocyte apoptosis or Red blood cell programmed death) is a type of apoptosis that occurs in injured erythrocytes (RBCs) due to various factors including hyperosmolarity, oxidative stress, energy depletion, heavy metals exposure or xenobiotics. Like apoptosis, eryptosis is characterized by cell shrinkage, membrane blebbing, activation of proteases, and phosphatidylserine exposure at the outer membrane leaflet.[1][2]

  1. ^ Repsold, Lisa; Joubert, Anna Margaretha (2018). "Eryptosis: An Erythrocyte's Suicidal Type of Cell Death". BioMed Research International. 2018: 1–10. doi:10.1155/2018/9405617. ISSN 2314-6133. PMC 5817309. PMID 29516014.
  2. ^ Pretorius, Etheresia; du Plooy, Jeanette N.; Bester, Janette (2016). "A Comprehensive Review on Eryptosis". Cellular Physiology and Biochemistry. 39 (5): 1977–2000. doi:10.1159/000447895. hdl:2263/58594. ISSN 1015-8987. PMID 27771701.

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Eryptosis

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Eryptosis (Erythrocyte apoptosis or Red blood cell programmed death) is a type of apoptosis that occurs in injured erythrocytes (RBCs) due to various...

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Red blood cell

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defective cells and continually purging the blood. This process is termed eryptosis, red blood cell programmed death. This process normally occurs at the...

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to mice. Under physiological concentrations, ursolic acid also induces eryptosis (the apoptosis-like suicidal cell death in defective red blood cells)...

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Programmed cell death

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another programmed form of necrosis that takes place in fibroblasts. Eryptosis is a form of suicidal erythrocyte death. Aponecrosis is a hybrid of apoptosis...

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Lang E, Föller M (October 2012). "Physiology and pathophysiology of eryptosis". Transfusion Medicine and Hemotherapy. 39 (5): 308–14. doi:10.1159/000342534...

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PAK2

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phosphorylation by AMP-activated protein kinase in stem and cancer cells and eryptosis. PAK2 is cleaved through activated caspase-3 in fibroblast and cancer...

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