Purification and cloning of factor VIII, gene therapy for haemophilia
Awards
Fellowship of the Academy of Medical Sciences, Barry Firkin Award 2006, Henri Chaigneau Award 2012
Scientific career
Fields
haematology
Institutions
University College London, Royal Free Hospital
Edward (Ted) G. D. Tuddenham FMedSci is considered one of the world's leading haematologists[citation needed] having authored over 200 papers in the field. He gained his Bachelor of Medicine, Bachelor of Surgery at the University of London in 1968 and his Membership of the Royal College of Physicians in 1975. Up until 2005 was head of the Haemostasis and Thrombosis Research (Medical Research Council) Group at Imperial College. Professor Tuddenham is a pioneer in the field of haemophilia and was responsible, along with Frances Rotblat, for the purification and cloning of the factor VIII gene, which led to the highly effective and safe treatments available to haemophilia sufferers today. In more recent years, he has been actively involved in developing gene therapy for haemophilia. The first successful use of gene transfer to convert severe to mild haemophilia B was reported by his group in December 2011.He retired from Directorship of the Katharine Dormandy Centre in July 2011 and is now Emeritus Professor of Haemophilia at University College London. He continues to work in the Haemophilia Centre at the Royal Free Hospital on gene therapy clinical trials, with the goal of curing all forms of haemophilia.
Edward (Ted) G. D. Tuddenham FMedSci is considered one of the world's leading haematologists[citation needed] having authored over 200 papers in the field...
purification by EdwardTuddenham, Frances Rotblat and coworkers led to the molecular identification of the protein. Ralph Kekwick Frances Rotblat Edward Shanbrom...
Sir Thomas Tuddenham (10 May 1401 – 23 February 1462) was an influential Norfolk landowner, official and courtier. He served as Steward of the Duchy of...
2021 from complications of diabetes. In 1979, Rotblat began work with EdwardTuddenham at the Royal Free Hospital in North London to isolate and stabilise...
he and Edward Maria Wingfield served 1569 & 1570s. [B]. FETTIPLACE, Michael. Came to Jamestown, 1608. Paid -L-12-10s–0d. Of, et al., Tuddenham, Suffolk...
eldest son and heir of John de Vere, 12th Earl of Oxford 1462 – Sir Thomas Tuddenham 1462 – William Tyrrell 1462 – John Montgomery 1470 – John Tiptoft, 1st...
beheaded on Tower Hill on 23 February 1462, together with Sir Thomas Tuddenham and John Montgomery. John de Vere, 12th Earl of Oxford, and his eldest...
located in the parish including Hiptofts, Jacketts, Tuddenham Hall and Bevis Hall. About 1400 Edward and John Hiptoft had a licence for an oratory in their...
Lincolnshire (1810–20) Rector of Dunton, Buckinghamshire (1811–17) Rector of Tuddenham, Suffolk (1817–20) Vicar and Rector of Little Chesterford, Essex (1817–24)...
Fiennes 1439–1446 John Stourton, 1st Baron Stourton 1446–1453 Sir Thomas Tuddenham 1458 Sir John Fogge 1461–1468 Sir John Howard 1468–1474. Sir John Elrington...
or Wotton (1536–1587). Anne was the daughter of John Wootton of North Tuddenham in Norfolk and the great-niece of Henry Wotton. Anne was the widow of...
Peter Tuddenham, the Worthing actor with all the answers – Littlehampton Today Archived 8 January 2009 at the Wayback Machine "Peter Tuddenham". The Independent...
lock, with his body in the boot. 141 "Smoke Gets in Your Eyes" Peter Tuddenham and John Ioannou guest star Christopher Hodson Jim Hawkins 7 December 1995 (1995-12-07)...
Rodska 14 February 1987 8 Poison John Fletcher Robert Tronson Alfred Burke, Bernard Archard, Peter Tuddenham, Philip Anthony, Philip Bond 21 February 1987...
Denman 4 December 1995 (1995-12-04) 141 "Smoke Gets in Your Eyes" Peter Tuddenham and John Ioannou guest star Christopher Hodson Jim Hawkins 7 December 1995 (1995-12-07)...
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