Protein-coding gene in the species Homo sapiens
ELL3 Identifiers Aliases ELL3 , ELL3 (gene), elongation factor for RNA polymerase II 3External IDs OMIM: 609885; MGI: 2673679; HomoloGene: 11859; GeneCards: ELL3; OMA:ELL3 - orthologs Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q15.3 Start 43,772,605 bp[1] End 43,777,315 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 E5 Start 121,269,491 bp[2] End 121,274,759 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum lymph node zone of skin skin of abdomen skin of leg mucosa of transverse colon left testis right testis rectum testicle
Top expressed in spleen morula proximal tubule epiblast primary oocyte embryo right kidney human kidney blastocyst zone of skin
More reference expression data
BioGPS
Gene ontology Molecular function Cellular component
nucleolus
transcription elongation factor complex
nucleus
nucleoplasm
Biological process
positive regulation of DNA-templated transcription, elongation
positive regulation of neurogenesis
positive regulation of neural precursor cell proliferation
transcription elongation from RNA polymerase II promoter
regulation of epithelial to mesenchymal transition
DNA-templated transcription, elongation
regulation of transcription, DNA-templated
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
transcription by RNA polymerase II
spermatogenesis
positive regulation of transcription by RNA polymerase II
stem cell differentiation
transcription, DNA-templated
negative regulation of signal transduction by p53 class mediator
snRNA transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 15: 43.77 – 43.78 Mb Chr 2: 121.27 – 121.27 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Elongation factor RNA polymerase II-like 3 is a protein that in humans is encoded by the ELL3 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000128886 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027246 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: Elongation factor RNA polymerase II-like 3".
Last Update: 2023-03-03T19:42:11Z
factor RNA polymerase II-like 3 is a protein that in humans is encoded by the ELL3 gene. GRCh38: Ensembl release 89: ENSG00000128886 – Ensembl, May 2017 GRCm38:...
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Last Update: 2024-03-10T03:36:12Z
CYP19A1: encoding protein Cytochrome p450 family 19 subfamily a member 1 DTWD1: ELL3 : encoding protein Elongation factor RNA polymerase II-like 3 FAH: fumarylacetoacetate...
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Last Update: 2023-08-18T11:08:23Z
(November 2017). "Selective expression of the transcription elongation factor ELL3 in B cells prior to ELL2 drives proliferation and survival". Mol. Immunol...
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Last Update: 2024-03-28T02:17:30Z
transcription. There are five paralogs of OCEL1 in this gene family: ELL, ELL2, ELL3 , MARVELD2, and OCLN. OCEL1 and each of its five paralogs all contain the...
Word Count : 1572