EIF3F information

EIF3F
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J8B, 3J8C
Identifiers
Aliases	EIF3F, EIF3S5, eIF3-p47, eukaryotic translation initiation factor 3 subunit F, MRT67
External IDs	OMIM: 603914; MGI: 1913335; HomoloGene: 2783; GeneCards: EIF3F; OMA:EIF3F - orthologs
EC number	3.4.19.12
Gene location (Human)
Chr.	Chromosome 11 (human)
End	8,001,862 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	108,542,158 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; skin of abdomen; ; body of pancreas; ; stromal cell of endometrium; ; canal of the cervix; ; gastric mucosa; ; body of stomach; ; left uterine tube; ; right uterine tube; ; transverse colon;
	Top expressed in
	Paneth cell; ; vas deferens; ; medial ganglionic eminence; ; hair follicle; ; utricle; ; internal carotid artery; ; fossa; ; external carotid artery; ; trigeminal ganglion; ; left lung lobe;
	More reference expression data
	n/a
Gene ontology
Molecular function	cysteine-type peptidase activity; translation initiation factor activity; thiol-dependent deubiquitinase; peptidase activity; protein binding; hydrolase activity; translation initiation factor binding;
Cellular component	cytoplasm; cytosol; eukaryotic translation initiation factor 3 complex; membrane; eukaryotic translation initiation factor 3 complex, eIF3m; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex;
Biological process	proteolysis; translational initiation; protein biosynthesis; IRES-dependent viral translational initiation; protein deubiquitination; formation of cytoplasmic translation initiation complex; cytoplasmic translational initiation;
	Sources:Amigo / QuickGO
Orthologs
	8665
	66085
	ENSG00000175390
	ENSMUSG00000031029
	O00303
	Q9DCH4
	NM_003754
	NM_025344
	NP_003745
	NP_079620
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a protein that in humans is encoded by the EIF3F gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175390 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031029 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
^ "Entrez Gene: EIF3S5 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175390 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031029 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9341143-5] Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.

[entrez-6] "Entrez Gene: EIF3S5 eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa".

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