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Dysembryoplastic neuroepithelial tumour information


Dysembryoplastic neuroepithelial tumour
DNET
SpecialtyNeuro-oncology, Neurosurgery

Dysembryoplastic neuroepithelial tumour (DNT, DNET) is a type of brain tumor. Most commonly found in the temporal lobe, DNTs have been classified as benign tumours.[1] These are glioneuronal tumours comprising both glial and neuron cells and often have ties to focal cortical dysplasia.[2]

Varying subclasses of DNTs have been presently identified, with dispute existing in the field on how to properly group these classes.[3] The identification of possible genetic markers to these tumours is currently underway.[4] With DNTs often causing epileptic seizures, surgical removal is a common treatment, providing high rates of success.[4]

  1. ^ Thom M, Toma A, An S, Martinian L, Hadjivassiliou G, Ratilal B, et al. (October 2011). "One hundred and one dysembryoplastic neuroepithelial tumors: an adult epilepsy series with immunohistochemical, molecular genetic, and clinical correlations and a review of the literature". Journal of Neuropathology and Experimental Neurology. 70 (10): 859–878. doi:10.1097/NEN.0b013e3182302475. PMID 21937911.
  2. ^ Suh YL (November 2015). "Dysembryoplastic Neuroepithelial Tumors". Journal of Pathology and Translational Medicine. 49 (6): 438–449. doi:10.4132/jptm.2015.10.05. PMC 4696533. PMID 26493957.
  3. ^ Komori T, Arai N (August 2013). "Dysembryoplastic neuroepithelial tumor, a pure glial tumor? Immunohistochemical and morphometric studies". Neuropathology. 33 (4): 459–468. doi:10.1111/neup.12033. PMID 23530928.
  4. ^ a b Chassoux F, Daumas-Duport C (December 2013). "Dysembryoplastic neuroepithelial tumors: where are we now?". Epilepsia. 54 (Suppl 9): 129–134. doi:10.1111/epi.12457. PMID 24328886.

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