A dual therapy stent is a coronary artery stent that combines the technology of an antibody-coated stent and a drug-eluting stent. [1] Currently, second-generation drug-eluting stents require long-term use of dual-antiplatelet therapy, which increases the risk of major bleeding occurrences in patients.[2] Compared to drug-eluting stents, dual therapy stents have improved vessel regeneration and cell proliferation capabilities. [1][2] As a result, dual therapy stents were developed to reduce the long-term need for dual-antiplatelet therapy.[3]
The COMBO stent is the first and only dual therapy stent that addresses the challenges of vessel healing in drug-eluting stents. [4] This stent is an anti-CD34 antibody-coated and sirolimus-eluting bioresorbable stent.[2] The COMBO stent combines the Genous stent's endothelial cell capture technology with an antiproliferative, biodegradable sirolimus drug elution.[5] The COMBO stent has received CE Mark approval.[6]
^ abCite error: The named reference :1 was invoked but never defined (see the help page).
^ abcCite error: The named reference :3 was invoked but never defined (see the help page).
^Baldetti, Luca; Beneduce, Alessandro; Gramegna, Mario; Colombo, Antonio; Giannini, Francesco (2018). "The dual-therapy COMBO stent: a rationale for a light dual antiplatelet therapy treatment". Future Cardiology. 14 (6): 471–482. doi:10.2217/fca-2018-0051. ISSN 1744-8298. PMID 30480466. S2CID 53730585. Archived from the original on 2021-11-18. Retrieved 2021-11-18.
^Cite error: The named reference :2 was invoked but never defined (see the help page).
^Baldetti, Luca; Beneduce, Alessandro; Gramegna, Mario; Colombo, Antonio; Giannini, Francesco (2018-11-01). "The dual-therapy COMBO stent: a rationale for a light dual antiplatelet therapy treatment". Future Cardiology. 14 (6): 471–482. doi:10.2217/fca-2018-0051. ISSN 1479-6678. PMID 30480466. S2CID 53730585. Archived from the original on 2024-03-16. Retrieved 2021-10-29.
^"First Dual-Therapy Stent Nets CE Mark". www.healio.com. Archived from the original on 2021-11-17. Retrieved 2021-11-17.
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A dualtherapystent is a coronary artery stent that combines the technology of an antibody-coated stent and a drug-eluting stent. Currently, second-generation...
coronary stents is in the coronary arteries, into which a bare-metal stent, a drug-eluting stent, a bioabsorbable stent, a dual-therapystent (combination...
received CE mark for the world's first and only dualtherapystent, the COMBO DualTherapyStent. The COMBO Stent features active endothelial progenitor cell...
Combo DualTherapyStent is a coronary stent that combines Genous with an antiproliferative, biodegradable sirolimus drug elution. The Combo Stent was shown...
However, in some cases the dual antiplatelet therapy may be insufficient to fully prevent clots that may result in stent thrombosis; these clots and...
coronary artery disease. The procedure is used to place and deploy coronary stents, a permanent wire-meshed tube, to open narrowed coronary arteries. PCI is...
single-drug therapy instead. More severe and complicated cases are treated with dual antiplatelet therapy, or in some cases triple therapy that includes...
acetylsalicylic acid (aspirin). Dual antiplatelet therapy (DAPT) is recommended for 1 month following bare metal stent placement, for 3 months following...
heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Its effect starts about two hours after...
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immunosuppressant used in drug-eluting stents. Zotarolimus is an immunosuppressant used in coronary drug-eluting stents. The second generation of mTOR inhibitors...
artery stenting is used for same side stroke prevention, basilar artery stenting may help to improve parallel, accessory blood flow. The stent may also...
examinations and therapy, including ablation and diagnostic catheters Vascular intervention: products for coronary and peripheral functions including stent systems...
used in patients in whom aspirin was not tolerated, or in whom dual antiplatelet therapy was desirable. With the advent of newer and safer antiplatelet...
Safety of Drug-Eluting Stents Optimized for Biocompatibility vs Bare-Metal Stents With a Single Month of Dual Antiplatelet Therapy". JAMA Cardiology. 3...
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immediate coronary stenting, and for bridging those surgery patients who require P2Y12 inhibition. Evidence regarding cangrelor therapy is limited by the...
benefits worth the associated risks. Clopidogrel plus aspirin (dual anti-platelet therapy) reduces cardiovascular events more than aspirin alone in those...
anti-platelet therapy, such as Aspirin, to reduce thrombus formation in pocket vortices associated with turbulent blood flow. Dual anti-platelet therapy and full...
current guidelines also recommend immediate administration of dual antiplatelet therapy upon diagnosis; clopidogrel and ticagrelor are indicated in this...
infarction treated with percutaneous coronary intervention and dual antiplatelet therapy". The American Journal of Cardiology. 106 (9): 1197–1200. doi:10...
require surgical intervention after initiation of medical therapy, with endovascular stent-grafting (TEVAR) available as a less invasive alternative to...
flow and determine a progressive thrombosis of the sac. Flow diverting stents consist of structural Cobalt-chrome or Nitinol alloy wires and often a set...
24-month duration of dual-antiplatelet therapy after stent implantation: a pre-specified analysis from the PRODIGY (Prolonging Dual-Antiplatelet Treatment...
those who have had a stent, more than 12 months of clopidogrel plus aspirin does not affect the risk of death. Beta blocker therapy such as metoprolol or...
formed a blood clot in her brain, but Andrews manages to remove it using a stent retriever. Morgan discovers that her patient has a tumor on his heart and...
radioembolization or selective internal radiation therapy (SIRT).[citation needed] Clinical trials determine what type of therapy is generally most successful for treating...
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