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Doxapram information


Doxapram
Clinical data
Routes of
administration
Intravenous
ATC code
  • R07AB01 (WHO)
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 1-ethyl-4- (2-morpholin-4-ylethyl)- 3,3-diphenyl-pyrrolidin-2-one
CAS Number
  • 309-29-5 checkY
PubChem CID
  • 3156
DrugBank
  • DB00561 checkY
ChemSpider
  • 3044 checkY
UNII
  • 94F3830Q73
KEGG
  • D07873 checkY
ChEBI
  • CHEBI:681848 checkY
ChEMBL
  • ChEMBL1754 checkY
CompTox Dashboard (EPA)
  • DTXSID2022963 Edit this at Wikidata
ECHA InfoCard100.005.653 Edit this at Wikidata
Chemical and physical data
FormulaC24H30N2O2
Molar mass378.516 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • O=C4N(CC)CC(CCN1CCOCC1)C4(c2ccccc2)c3ccccc3
InChI
  • InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3 checkY
  • Key:XFDJYSQDBULQSI-UHFFFAOYSA-N checkY
  (verify)

Doxapram hydrochloride (marketed as Dopram, Stimulex or Respiram) is a respiratory stimulant, or analeptic. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate.

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Doxapram

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Doxapram hydrochloride (marketed as Dopram, Stimulex or Respiram) is a respiratory stimulant, or analeptic. Administered intravenously, doxapram stimulates...

Word Count : 330

Analeptic

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term "analeptic" typically refers to respiratory stimulants (for example, doxapram). Analeptics are central nervous system (CNS) stimulants that include a...

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Respiratory failure

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immediately or otherwise if NIV fails. Respiratory stimulants such as doxapram are now rarely used. There is tentative evidence that in those with respiratory...

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Hypercapnia

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in preference to invasive mechanical ventilation. In the past, the drug doxapram (a respiratory stimulant), was used for hypercapnia in acute exacerbation...

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Opioid

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the only respiratory stimulant currently approved for this purpose is doxapram, which has only limited efficacy in this application. Newer drugs such...

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Xylazine

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xylazine in animals were also reversed by the analeptics 4-aminopyridine, doxapram, and caffeine, which are physiological antagonists to central nervous system...

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Schedule H

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HYDROCHLORIDE 163. DOPAMINE HYDROCHLORIDE 164. DOTHIEPIN HYDROCHLORIDE 165. DOXAPRAM HYDROCHLORIDE 166. DOXAZOSIN MESYLATE 167. DOXEPIN HYDROCHLORIDE 168. DOXORUBICIN...

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ATC code R07

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Colfosceril palmitate R07AA02 Natural phospholipids R07AA30 Combinations R07AB01 Doxapram R07AB02 Nikethamide R07AB03 Pentetrazol R07AB04 Etamivan R07AB05 Bemegride...

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General anaesthesia

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clonic activity (shivering). This theory is supported by the fact that doxapram, a CNS stimulant, is somewhat effective in abolishing postoperative shivering...

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C24H30N2O2

Last Update:

C24H30N2O2 (molar mass: 378.51 g/mol) may refer to: Desmethylmoramide Doxapram Tetrahydrofuranylfentanyl This set index page lists chemical structure...

Word Count : 51

Amiphenazole

Last Update:

largely been replaced by more effective respiratory stimulants such as doxapram and specific opioid antagonists such as naloxone. Worlock A (November 1956)...

Word Count : 371

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