Douglas C. Prasher (born August 1951) is an American molecular biologist. He is known for his work to clone and sequence the genes for the photoprotein aequorin[1] and green fluorescent protein (GFP)[2] and for his proposal to use GFP as a tracer molecule.[3] He communicated his pioneering work to Martin Chalfie and Roger Y. Tsien, but by 1991 he was unable to obtain further research funding, and left academia. Eventually, he had to abandon science. Chalfie and Tsien were awarded the 2008 Nobel Prize in Chemistry for work that they publicly acknowledged was substantially based on Prasher's work; through their efforts and those of others, he returned to scientific research in June 2010.
^Prasher, D C; R O McCann; M Longiaru; M J Cormier (1987-03-10). "Sequence comparisons of complementary DNAs encoding aequorin isotypes". Biochemistry. 26 (5): 1326–1332. doi:10.1021/bi00379a019. ISSN 0006-2960. PMID 2882777.
^Prasher, D C; V K Eckenrode; W W Ward; F G Prendergast; M J Cormier (1992-02-15). "Primary structure of the Aequorea victoria green-fluorescent protein". Gene. 111 (2): 229–233. doi:10.1016/0378-1119(92)90691-H. ISSN 0378-1119. PMID 1347277.
^Prasher, D C (August 1995). "Using GFP to see the light". Trends in Genetics. 11 (8): 320–323. doi:10.1016/s0168-9525(00)89090-3. ISSN 0168-9525. PMID 8585130.
Douglas C. Prasher (born August 1951) is an American molecular biologist. He is known for his work to clone and sequence the genes for the photoprotein...
that he had put forward Shimomura and Prasher to the Nobel Committee in 2004. Chalfie stated, "DouglasPrasher's work was critical and essential for the...
1992 when DouglasPrasher reported the cloning and nucleotide sequence of wtGFP in Gene. The funding for this project had run out, so Prasher sent cDNA...
photoproteins that cause bioluminescence in this species. Three decades later, DouglasPrasher sequenced and cloned the gene for GFP. Martin Chalfie figured out how...
Osamu Shimomura in the 1960s and was developed as a tracer molecule by DouglasPrasher in 1987. FPs led to a breakthrough of live cell imaging with the ability...
glaciologist (M.S., Ph.D.) Roy Plunkett, inventor of teflon (Ph.D. 1936) DouglasPrasher, discoverer of green fluorescent protein (GFP) gene (Ph.D. 1979) Karl...
ISSN 0036-8075. PMID 20448176. S2CID 2375135. O'Kane, Dennis J.; Prasher, Douglas C. (1992-02-01). "Evolutionary origins of bacterial bioluminescence"...
Ordnance Survey. Samuel Robert Douglas Power, Chief Mechanical and Electrical Engineer, Paddington, British Rail. Richard Prasher. For services to the environment...
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