This article is about compounds with two SH functional groups. For other uses, see dithiole.
In organic chemistry, a dithiol is a type of organosulfur compound with two thiol (−SH) functional groups. Their properties are generally similar to those of monothiols in terms of solubility, odor, and volatility. They can be classified according to the relative location of the two thiol groups on the organic backbone.
Structure of some dithiols
Benzene-1,2-dithiol, the parent aromatic dithiol
Propane-1,3-dithiol
The drug meso-2,3-dimercaptosuccinic acid
Dimercaprol ("British anti-Lewisite"), an early antidote for arsenic poisoning
In organic chemistry, a dithiol is a type of organosulfur compound with two thiol (−SH) functional groups. Their properties are generally similar to those...
the formula (CH(OH)CH2SH)2. A colorless compound, it is classified as a dithiol and a diol. DTT is redox reagent also known as Cleland's reagent, after...
DMPS, another dithiol, as a mercury-chelating agent. The Soviets also introduced ALA, which is transformed by the body into the dithiol dihydrolipoic...
part of a highly conserved CXXC motif, that can cycle between an active dithiol form (reduced) and an oxidized disulfide form. In its active state, thioredoxin...
up to a quarter of a mile [0.40 km], and one drop of either acetone gem-dithiol or the mother liquors from crude trithioacetone crystallisations were placed...
This carboxylic acid features a pair of thiol groups, and therefore is a dithiol. It is optically active, but only the R-enantiomer is biochemically significant...
2005.05.004. PMID 16009427. Rooney JP (May 2007). "The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury"...
aldehyde is activated by conversion to cyclic dithioacetal by reaction with a dithiol (nucleophilic substitution) in presence of a H+ donating acid. The cyclic...
and in animals (thioredoxin reductase) generates reduced thioredoxin, a dithiol that serves as an electron source for peroxidases and also the important...
a melting point of 75.7–76.5 °C, higher than that of the corresponding dithiol: dihydroasparagusic acid (or γ,γ-dimercaptoisobutyric acid), at 59.5–60...
of the RNR1 and RNR2 subunits. The active site consists of the active dithiol groups from the RNR1 as well as the diferric center and the tyrosyl radical...
Chandrasekaran, James P. Donahue (2009). "Synthesis of 4,5-Dimethyl-1,3-Dithiol-2-One". Organic Syntheses. 86: 333. doi:10.15227/orgsyn.086.0333. Millican...
engineered protein could exist in two different oxidation states (reduced dithiol or oxidized disulfide), each with different fluorescent properties. Originally...
Dithiobutylamine Names Preferred IUPAC name (S)-2-aminobutane-1,4-dithiol Other names DTBA Identifiers CAS Number 1363594-47-1(2S) 1363376-98-0 (hydrochloride)...
Global Information
Benzene-1,2-dithiol, the parent aromatic dithiol
Propane-1,3-dithiol
The drug meso-2,3-dimercaptosuccinic acid
Dimercaprol ("British anti-Lewisite"), an early antidote for arsenic poisoning
Dihydrolipoic acid, a vitamin
Dithiothreitol, a reagent in protein biochemistry
