Global Information Lookup Global Information

Dithiobutylamine information


Dithiobutylamine[1]
Skeletal formula of dithiobutylamine
Names
Preferred IUPAC name
(S)-2-aminobutane-1,4-dithiol
Other names
DTBA
Identifiers
CAS Number
  • 1363594-47-1(2S)
  • 1363376-98-0 (hydrochloride)
3D model (JSmol)
  • Interactive image
ChemSpider
  • 32696684
PubChem CID
  • 89734616
InChI
  • InChI=1S/C4H11NS2/c5-4(3-7)1-2-6/h4,6-7H,1-3,5H2/t4-/m0/s1
    Key: VGLCUHJZKWYDPC-BYPYZUCNSA-N
SMILES
  • SC[C@H](CCS)N
Properties
Chemical formula
C4H11NS2
Molar mass 137.26 g/mol
Appearance White solid[1]
Odor Nearly odorless[1]
Solubility in water
Soluble
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dithiobutylamine (DTBA) is a reducing agent intended as an alternative for DTT in biochemical uses. It was designed to be easily synthesized in non-racemic form, to have a lower pKa (allowing more effective reduction at neutral pH), and to have a low disulfide E°′ reduction potential.[1] It was rationally designed & reported in 2012.[1] It is commercially available.

  1. ^ a b c d e Lukesh, John C.; Palte, Michael J.; Raines, Ronald T. (2012-02-21). "A Potent, Versatile Disulfide-Reducing Agent from Aspartic Acid". Journal of the American Chemical Society. 134 (9). American Chemical Society (ACS): 4057–4059. doi:10.1021/ja211931f. ISSN 0002-7863. PMC 3353773. PMID 22353145.

and 3 Related for: Dithiobutylamine information

Request time (Page generated in 0.5459 seconds.)

Dithiobutylamine

Last Update:

Dithiobutylamine (DTBA) is a reducing agent intended as an alternative for DTT in biochemical uses. It was designed to be easily synthesized in non-racemic...

Word Count : 113

Dithiothreitol

Last Update:

potent nucleophile as the pH falls. (2S)-2-Amino-1,4-dimercaptobutane (dithiobutylamine or DTBA), a related dithiol reducing agent, somewhat overcomes this...

Word Count : 872

TCEP

Last Update:

in phosphate buffers. 2-Mercaptoethanol (BME) Dithiothreitol (DTT) Dithiobutylamine (DTBA) TCEP technical information, from Interchim Shafer, D. E., Inman...

Word Count : 845

PDF Search Engine © AllGlobal.net