Red depicts the preferentially affected areas in distal myopathy.
Specialty
Neurology, neuromuscular medicine
Symptoms
Weakness of hands and/or feet
Complications
Cardiomyopathy
Usual onset
Variable
Duration
Lifetime
Types
Classic, myofibrillar myopathy, other
Causes
Genetic mutation of various genes
Diagnostic method
Genetic testing, muscle biopsy
Frequency
Rare
Distal myopathy is a group of rare genetic disorders that cause muscle damage and weakness, predominantly in the hands and/or feet. Mutation of many different genes can be causative. Many types involve dysferlin.[1]
^Murakami N, Sakuta R, Takahashi E, et al. (December 2005). "Early onset distal muscular dystrophy with normal dysferlin expression". Brain Dev. 27 (8): 589–91. doi:10.1016/j.braindev.2005.02.002. PMID 16310593. S2CID 28957231.
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