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Dinitrophenyl information


Dinitrophenyl is any chemical compound containing two nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation.[1][2] Dinitrophenyl does not elicit any immune response on its own and it does not bind to any antigen.[3]

  1. ^ Berd, D; Maguire Jr, H. C.; Mastrangelo, M. J.; Murphy, G (1994). "Activation markers on T cells infiltrating melanoma metastases after therapy with dinitrophenyl-conjugated vaccine". Cancer Immunology, Immunotherapy. 39 (3): 141–7. doi:10.1007/s002620050105. PMID 7923243.
  2. ^ Manne, J; Mastrangelo, M. J.; Sato, T; Berd, D (2002). "TCR rearrangement in lymphocytes infiltrating melanoma metastases after administration of autologous dinitrophenyl-modified vaccine". Journal of Immunology. 169 (6): 3407–12. doi:10.4049/jimmunol.169.6.3407. PMID 12218163.
  3. ^ "Dinitrophenyl". NCI Drug Dictionary. National Cancer Institute.

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Dinitrophenyl

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Dinitrophenyl is any chemical compound containing two nitro functional groups attached to a phenyl ring. It is a hapten used in vaccine preparation. Dinitrophenyl...

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Protein sequencing

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of peptide end-group analysis: A derivatization of N-terminal end with Sanger's reagent (DNFB), B total acid hydrolysis of the dinitrophenyl peptide...

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Zincke reaction

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chemical element zinc. The first reaction is the formation of the N-2,4-dinitrophenyl-pyridinium salt (2). This salt is typically isolated and purified by...

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Etonitazene

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to form N-(β-Diethylaminoethyl)-2,4-dinitroaniline [aka: N'-(2,4-Dinitrophenyl)-N,N-diethyl-ethane-1,2-diamine]. The 2-nitro substituent o n the 2...

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Nitrocefin

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Nitrocefin Identifiers IUPAC name (6R,7R)-3-[(E)-2-(2,4-dinitrophenyl)ethenyl]- 8-oxo-7-[(2-thiophen-2-ylacetyl)amino]- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-...

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Sivifene

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Routes of administration Topical Identifiers IUPAC name 4-[[2-(2,4-Dinitrophenyl)hydrazinyl]-(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one CAS...

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Frederick Sanger

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peptide determined by complete acid hydrolysis and discovering which dinitrophenyl-amino acid was there. By repeating this type of procedure Sanger was...

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Nitrazine

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Nitrazine Names IUPAC name (3E)-3-[(2,4-Dinitrophenyl)hydrazono]-4-oxonaphthalene-2,7-disulfonic acid Other names Nitrazine yellow; Phenaphthazine Identifiers...

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Peroxyoxalate

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4,5-trichlorophenyl-6-carbopentoxyphenyl)oxalate (CPPO) and bis(2,4-dinitrophenyl) oxalate (DNPO). Other aryl oxalates have been synthesized and evaluated...

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Binapacryl

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6-dinitrophenyl 3-methylbut-2-enoate Other names 2-[(2RS)-Butan-2-yl]-4,6-dinitrophenyl 3-methylbut-2-enoate (RS)-2-(Butan-2-yl)-4,6-dinitrophenyl 3-methylbut-2-enoate...

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Zincke aldehyde

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the terminal iminium group hydrolyzed to an aldehyde. The use of the dinitrophenyl group for pyridine activation was first reported by Theodor Zincke....

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Aziridines

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a mono-, di-, tri- or tetra-substituted alkene (olefin) with O-(2,4-dinitrophenyl)hydroxylamine (DPH) [de] in the presence of rhodium catalysts. Alkene...

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DNPO

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DNPO may refer to: Bis(2,4-dinitrophenyl) oxalate, a chemical used in glowsticks Dinitrogen pentoxide, an inorganic chemical compound DNPO, the ICAO airport...

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Sacoglottis gabonensis

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additives, on the metabolic and haematological side effects of 2,4-dinitrophenyl hydrazine-induced tissue damage". Vascular Pharmacology. 39 (6): 317–324...

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Bergmann degradation

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G.; Reith, W.S. (1953). "The synthesis of 3-(4'-dimethylamino-3:'5'-dinitrophenyl)hydantoin derivatives of various amino acids and their use for the determination...

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Acetoacetate decarboxylase

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was assessed through the hydrolysis of the synthetic substrate 2,4-dinitrophenyl propionate to dinitrophenol by acetoacetate decarboxylase. In the presence...

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