Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Difluoroacetic acid is a chemical compound with formula CHF2COOH. It is a dihalogenocarboxylic acid, specifically a structural analog of acetic acid with two of three hydrogen atoms on the alpha carbon replaced with fluorine atoms. In solution, it dissociates to form difluoroacetate ions. Difluoroacetic acid can also be used as direct C-H difluoromethylating reagent.[2]
^ abc"Difluoroacetic acid". Sigma-Aldrich.
^Tung, Truong Thanh; Christensen, Søren Brøgger; Nielsen, John (2017). "Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds". Chemistry - A European Journal. 23 (72): 18125–18128. doi:10.1002/chem.201704261. PMID 28945302.
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Difluoroaceticacid is a chemical compound with formula CHF2COOH. It is a dihalogenocarboxylic acid, specifically a structural analog of acetic acid with...
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cycle stops working. In contrast with fluoroacetic acid, difluoroaceticacid and trifluoroacetic acid are far less toxic. Its pKa is 2.66, in contrast to...
Dichloroacetic acid (DCA), sometimes called bichloroacetic acid (BCA), is the organic compound with formula CHCl2CO2H. It is an analogue of acetic acid, in which...
carboxylic acid is an organic acid that contains a carboxyl group (−C(=O)−OH) attached to an R-group. The general formula of a carboxylic acid is often...
oxidised in the liver, producing fluoride ions and difluoromethoxy-difluoroaceticacid. This is significantly higher than the metabolism of its structural...