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Deoxyguanosine diphosphate information


Deoxyguanosine diphosphate
Skeletal formula of deoxyguanosine diphosphate
Space-filling model of the deoxyguanosine diphosphate anion
Names
IUPAC name
2′-Deoxyguanosine 5′-(trihydrogen diphosphate)
Systematic IUPAC name
[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl trihydrogen diphosphate
Other names
dGDP; 2'-Deoxyguanosine-5'-diphosphate; 2'-Deoxy-GDP; 5'-dGDP
Identifiers
CAS Number
  • 3493-09-2 ☒N
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:28862 ☒N
ChemSpider
  • 388359 ☒N
DrugBank
  • DB03491
PubChem CID
  • 439220
InChI
  • InChI=1S/C10H15N5O10P2/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1 ☒N
    Key: CIKGWCTVFSRMJU-KVQBGUIXSA-N ☒N
  • InChI=1/C10H15N5O10P2/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1
    Key: CIKGWCTVFSRMJU-KVQBGUIXBA
SMILES
  • O=P(O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n1cnc2c1NC(=N/C2=O)\N)C[C@@H]3O
Properties
Chemical formula
 C10H15N5O10P2
Molar mass 427.203 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Deoxyguanosine diphosphate (dGDP) is a nucleoside diphosphate. It is related to the common nucleic acid guanosine triphosphate (GTP), with the -OH group on the 2' carbon on the nucleotide's pentose removed (hence the deoxy- part of the name), and with one fewer phosphoryl group than GTP.[1]

  1. ^ "2'-Deoxyguanosine-5'-Diphosphate". DrugBank.

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Deoxyguanosine diphosphate

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C10H15N5O10P2

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formula C10H15N5O10P2 may refer to: Adenosine diphosphate Adenosine 3',5'-bisphosphate Deoxyguanosine diphosphate This set index page lists chemical structure...

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expressed only in dividing cells. The DGUOK gene encodes for mitochondrial deoxyguanosine kinase (dGK), which catalyzes the phosphorylation of deoxyribonucleosides...

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cytidine 5’-diphosphate (CDP) and uridine 5’-diphosphate (UDP); 2’-deoxyguanosine 5’-triphosphate (dGTP) induces reduction of adenosine 5’-diphosphate (ADP);...

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infected cells. Ganciclovir triphosphate is a competitive inhibitor of deoxyguanosine triphosphate (dGTP). It is incorporated into viral DNA and preferentially...

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superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative...

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there are about 2,400 oxidatively damaged guanines that form 8-oxo-2'-deoxyguanosine (8-OHdG) in the average mammalian cell DNA. 8-OHdG constitutes about...

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triphosphate, TMP is (deoxy)thymidine monophosphate and ADP is adenosine diphosphate. Thymidine kinases have a key function in the synthesis of DNA and therefore...

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phosphorylate other preformed nucleosides, specifically deoxyadenosine (dA) and deoxyguanosine (dG), and convert them into their monophosphate forms. There has been...

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cellular death. In a rat animal model, urine levels of 8-hydroxy-2'-deoxyguanosine (as a biomarker of DNA damage byreactive oxygen species) were measured...

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