DNA footprinting is a method of investigating the sequence specificity of DNA-binding proteins in vitro. This technique can be used to study protein-DNA interactions both outside and within cells.
The regulation of transcription has been studied extensively, and yet there is still much that is unknown. Transcription factors and associated proteins that bind promoters, enhancers, or silencers to drive or repress transcription are fundamental to understanding the unique regulation of individual genes within the genome. Techniques like DNA footprinting help elucidate which proteins bind to these associated regions of DNA and unravel the complexities of transcriptional control.
DNAfootprinting is a method of investigating the sequence specificity of DNA-binding proteins in vitro. This technique can be used to study protein-DNA...
A DNase footprinting assay is a DNAfootprinting technique from molecular biology/biochemistry that detects DNA-protein interaction using the fact that...
transcription factors across the genome. DNAfootprinting is a method aimed at identifying protein-bound DNA. It uses labeling and fragmentation coupled...
a protein bound to DNA within a DNA-protein complex. In DNAfootprinting the protein is envisioned to make an imprint (or footprint) at a particular point...
available from military personnel's remains, DNA and dental records are used to confirm identity. Footprints have been preserved as fossils and provide...
in vitro using synthetic DNA arrays of the strong '601' nucleosome positioning element. Nuclease digestion and DNAfootprinting experiments suggest that...
RNA-binding proteins. It is different from the more commonly used DNAfootprinting assay. The toeprinting assay has been utilized to examine the formation...
the DNA of interest and multiple primers annealing to the DNA linkers; it has been used for DNA sequencing, genome walking, and DNAfootprinting. Methylation-specific...
binds to non specific DNA sequences whilst having a 20 fold higher affinity for loxP sequences and results of early DNAfootprinting studies also suggested...
such technique is Phylogenetic Footprinting. Phylogenetic footprinting relies upon two major concepts: The function and DNA binding preferences of transcription...
Touch DNA, also known as Trace DNA, is a forensic method for analyzing DNA left at the scene of a crime. It is called "touch DNA" because it only requires...
the target fragments. This method is deployed for DNA sequencing, genome walking, and DNAfootprinting. A related technique is amplified fragment length...
vitro using small molecule donors like acetyl phosphate. Phylogenetic footprinting is a technique that utilizes multiple sequence alignments to determine...
with DNase footprinting, primer extension, and promoter-probe experiments when studying transcription initiation, DNA gang replication, DNA repair or RNA...
Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring...
Environmental DNA or eDNA is DNA that is collected from a variety of environmental samples such as soil, seawater, snow or air, rather than directly sampled...
nanoplasmonic molecular ruler for measuring nuclease activity and DNAfootprinting". Nature Nanotechnology. 1 (1). Springer Science and Business Media...
inferred from gel electrophoresis, FRET, and hydroxyl radical and nuclease footprinting studies. In the 1990s, crystallography and nucleic acid NMR methods became...
Chloroplast DNA Interactive gene map of chloroplast DNA from Nicotiana tabacum. Segments with labels on the inside reside on the B strand of DNA, segments...
functionality for these two enzymes. Footprinting indicates that gyrase, which forms a 140-base-pair footprint and wraps DNA, introduces negative supercoils...
Global Information