A branch of pathology that studies and diagnoses diseases on the cellular level
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A pair of micrographs of a cytopathology specimen showing a 3-dimensional cluster of cancerous cells (serous carcinoma)An adenocarcinoma with typical features as can be seen on cytopathology
Cytopathology (from Greek κύτος, kytos, "a hollow";[1]πάθος, pathos, "fate, harm"; and -λογία, -logia) is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues. Cytopathology is frequently, less precisely, called "cytology", which means "the study of cells".[2]
Cytopathology is commonly used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer but also in the diagnosis of some infectious diseases and other inflammatory conditions.[3] For example, a common application of cytopathology is the Pap smear, a screening tool used to detect precancerous cervical lesions that may lead to cervical cancer.
Cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscope slide[4] for subsequent staining and microscopic examination. However, cytology samples may be prepared in other ways, including cytocentrifugation. Different types of smear tests may also be used for cancer diagnosis. In this sense, it is termed a cytologic smear.[5]
Micrograph of a pilocytic astrocytoma, showing characteristic bipolar cells with long pilocytic (hair-like) processes. Smear preparation. H&E stain
^Kirkpatrick; et al. (1989). The Cassell Concise English Dictionary. London. p. 324. ISBN 0-304-31806-X.{{cite book}}: CS1 maint: location missing publisher (link)
^"Cytology". Collection development manual of the National Library of Medicine (4th ed.). Bethesda, MD: National Library of Medicine, National Institutes of Health, U.S. Department of Health and Human Services. 2004.
^"Cytopathology Specialty Description". American Medical Association. Retrieved 30 August 2020.
^Stedman's medical dictionary (27th ed.). Lippincott Williams & Wilkins. 2006. ISBN 978-0683400076.
^Chapter 13, section of squamous cell carcinomas, in Mitchell, Richard Sheppard; Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2007). Robbins Basic Pathology (8th ed.). Philadelphia: Saunders. ISBN 978-1-4160-2973-1.
Cytopathology (from Greek κύτος, kytos, "a hollow"; πάθος, pathos, "fate, harm"; and -λογία, -logia) is a branch of pathology that studies and diagnoses...
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on the basis of the involved sample types (comparing, for example, cytopathology, hematopathology, and histopathology), organs (as in renal pathology)...
head and neck, dermatopathology), neuropathology, hematopathology cytopathology, and forensic pathology. To be licensed to practice pathology, one has...
Cancer Cytopathology is a monthly peer-reviewed scientific journal which covers practice of cytopathology and its related oncology-based disciplines. It...
digestion, excretion, and respiration. In medical fields, especially cytopathology, serous fluid is a synonym for effusion fluids from various body cavities...
a Greek physician, zoologist and microscopist who was a pioneer in cytopathology and early cancer detection, and inventor of the "Pap smear". After studying...
Bethesda system used for cytopathology of thyroid nodules, which is called The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC or BSRTC). Like...
The American Society of Cytopathology (ASC), founded in 1951, is a national professional society of physicians, cytotechnologists and scientists who are...
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and timing of the process. Pap staining is usually associated with cytopathology in which loose cells are examined, but the stain has also been modified...
but similar stains widely used in hematology (the study of blood) and cytopathology (the study of diseased cells). Romanowsky-type stains are used to differentiate...
refers to abnormal appearance of cell nuclei. It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic. Nuclear atypia...
Society of Cytopathology (ASC) guidelines. Other countries have their own versions of the ASCT, including the British Association of Cytopathology (BAC) in...
studies and diagnoses diseases on the cellular level is called cytopathology. Cytopathology is generally used on samples of free cells or tissue fragments...
2022-10-13. Retrieved 2024-02-25. DeMay, M. (2007). Practical principles of cytopathology. Revised edition. Chicago, IL: American Society for Clinical Pathology...
of cytopathology. Dr. Koprowska was a founding member of the Inter Society Council of Cytology, which became the American Society of Cytopathology. Additionally...
) X-rays, Ultrasounds, and other imaging methods of affected joints Cytopathology and chemical pathology of fluid aspirated from affected joints (e.g...
medicine Pathology Anatomical Clinical pathology Clinical chemistry Cytopathology Medical microbiology Transfusion medicine Other Addiction medicine Adolescent...
Peritoneal mesothelioma Micrograph of a cytopathology specimen showing mesothelioma. The cytopathologic appearance of mesothelioma in the pleural cavity...
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