Footnotes / references Financials as of December 31, 2023[update].[1]
Cytokinetics, Incorporated, is a biopharmaceutical company based in South San Francisco, California, that develops muscle activators and muscle inhibitors as potential treatments for people with diseases characterized by impaired or declining muscle function.
^"Cytokinetics Reports Fourth Quarter 2023 Financial Results". Cytokinetics. 29 February 2024. Retrieved 29 February 2024.
Aficamten (CK-274) is a cardiac myosin inhibitor developed by Cytokinetics for the treatment of obstructive hypertrophic cardiomyopathy. Chuang, Chihyuan;...
of animal cell cytokinesis involves division plane specification and cytokinetic furrow formation. Precise positioning of the division plane between the...
December 2014, Astellas expanded its 18-month-old collaboration with Cytokinetics, focusing on the R&D and commercialization of skeletal muscle activators...
In molecular biology, an actomyosin ring or contractile ring, is a prominent structure during cytokinesis. It forms perpendicular to the axis of the spindle...
Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is an Fc receptor which facilitates...
Amgen also announced that it would terminate its collaboration with Cytokinetics and transition the development and commercialization rights for omecamtiv...
S2CID 9411257. Mast J (9 October 2020). "R&D Amgen's big cardiovascular bet with Cytokinetics hits PhIII primary but dramatically disappoints investors". Endpoints...
important model organism), actin forms cortical patches, actin cables, and a cytokinetic ring and the cap. Cortical patches are discrete actin bodies on the membrane...
Reldesemtiv (CK-2127107, CK-107) is a skeletal troponin activator developed by Cytokinetics in cooperation with Astellas. The drug aims at increasing muscle reactivity...
unconventional myosin VIII in plant cells and its localization at the post-cytokinetic cell wall". Plant Journal. 19 (5): 555–569. doi:10.1046/j.1365-313x.1999...
unconventional myosin VIII in plant cells and its localization at the post-cytokinetic cell wall". The Plant Journal. 19 (5): 555–567. doi:10.1046/j.1365-313X...
recruited to similar nodes; these nodes eventually condense to form the cytokinetic ring. A previously uncharacterized protein, Blt1, was found to colocalize...
Review of Cell and Developmental Biology. In 1998 Spudich co-founded Cytokinetics Inc. in San Francisco, along with Ron Vale and James Sabry from UCSF...
Here, the actin-bundling protein anillin drives actin contractility in cytokinetic rings. Some forces that are generally regarded as conventional forces...
mDia1 is highly homologous to Drosophila diaphanous, regulating the cytokinetic ring during cytokinesis. Homologues in other species are known as well...
Divergent Cellular Role for the FUSED Kinase Family in the Plant-Specific Cytokinetic Phragmoplast". Current Biology. 15 (23): 2107–2111. doi:10.1016/j.cub...
Squibb Camurus Catalyst Pharmaceuticals CRISPR Therapeutics CSL Behring Cytokinetics Daiichi Sankyo Editas Medicine Eli Lilly and Company Foundation Medicine...
binding pocket or to the FtsA-FtsA interface. FtsA localizes to the cytokinetic ring formed by FtsZ (Z ring). One of FtsA's functions in cytokinesis...
serving on the scientific advisory board of PTC, he does likewise with Cytokinetics and Solid Biosciences He is also on the scientific advisory board of...
migration microtubule-based movement positive regulation of mitotic cytokinetic process neural tube closure protein localization to microtubule regulation...
5 (Astrin) whose inappropriate accumulation at the midbody triggers cytokinetic arrest, multinucleated cells, and cell death. MID2 has been shown to...
actin. PRC1’s role in midzone microtubule formation, essential to the cytokinetic machinery of mammals, is made possible through its collaboration with...
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US$7.53 million (2023)