Crossover junction endodeoxyribonuclease information
Crossover junction endodeoxyribonuclease
Identifiers
EC no.
3.1.22.4
CAS no.
99676-43-4
Databases
IntEnz
IntEnz view
BRENDA
BRENDA entry
ExPASy
NiceZyme view
KEGG
KEGG entry
MetaCyc
metabolic pathway
PRIAM
profile
PDB structures
RCSB PDB PDBe PDBsum
Search
PMC
articles
PubMed
articles
NCBI
proteins
Holliday junction resolvases
Identifiers
Symbol
PDDEXK
Pfam clan
CL0236
Crossover junction endodeoxyribonuclease, also known as Holliday junction resolvase, Holliday junction endonuclease, Holliday junction-cleaving endonuclease, Holliday junction-resolving endoribonuclease, crossover junction endoribonuclease, and cruciform-cutting endonuclease, is an enzyme involved in DNA repair and homologous recombination. Specifically, it performs endonucleolytic cleavage that results in single-stranded crossover between two homologous DNA molecules at the Holliday junction to produce recombinant DNA products for chromosomal segregation. This process is known as Holliday junction resolution.
and 8 Related for: Crossover junction endodeoxyribonuclease information
Crossoverjunctionendodeoxyribonuclease, also known as Holliday junction resolvase, Holliday junction endonuclease, Holliday junction-cleaving endonuclease...
the RuvA tetramer. RuvC (Crossoverjunctionendodeoxyribonuclease RuvC) is the resolvase, which cleaves the Holliday junction. RuvC proteins have been...
Crossoverjunction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. It forms a complex with MUS81 which resolves Holliday junctions...
to damage sites. The CX3 complex was shown to associate with Holliday junction resolvase activity, probably in a role of stabilizing gene conversion tracts...
Crossoverjunction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene. In mammalian somatic cells, MUS81 and another structure...
recruitment to damage sites. The CX3 complex associates with Holliday junction resolvase activity, probably in a role of stabilizing gene conversion tracts...
different multiprotein complexes. The SLX1-SLX4 complex acts as a Holliday junction resolvase. As such, the complex cleaves the links between two homologous...
Global Information