Substance which creates inflammation in one area for reducing irritation in another body part
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A counterirritant is a substance which creates irritation or mild inflammation in one location with the goal of lessening discomfort and/or inflammation in another location.[1] This strategy falls into the more general category of counterstimulation.
Topical counter-irritants are non-analgesic, non-anesthetic substances or treatments used to treat pain. Capsaicin, menthol (mint oil), methyl salicylate, and camphor are examples of counterirritants. Heat and cold therapy and massage relieve pain by counterstimulation.[citation needed]
The US Food and Drug Administration defines a counterirritant as "An externally applied substance that causes irritation or mild inflammation of the skin for the purpose of relieving pain in muscles, joints and viscera distal to the site of application. They differ from the anesthetics, analgesics, and antipruritic agents, however, in that the pain relief they produce results from stimulation—rather than depression—of the cutaneous sensory receptors and occurs in structures of the body other than the skin areas to which they are applied as for example, in joints, muscles, tendons and certain viscera. The use of these products dates from antiquity."[2]
^"Definition of Counterirritant". Merriam Webster. Archived from the original on 14 March 2022. Retrieved 14 March 2022.
^Federal Register | Vol. 44, No. 234. California (CA): Food and Drug Administration (FDA). 4 December 1979. Archived from the original on 14 March 2022.
A counterirritant is a substance which creates irritation or mild inflammation in one location with the goal of lessening discomfort and/or inflammation...
alcohol, acetone, or similar quickly evaporating solvents and contain counterirritant aromatic chemical compounds, such as methyl salicylate, benzoin resin...
main ingredients in the patches. These include patches containing counterirritants, which are used to treat mild to moderate pain, and patches containing...
assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation...
help of a chemical called cineole, which is employed topically as a counterirritant. It is an ingredient in some liniments for sore muscles, such as Tiger...
cool sensation when applied gently, indicating its properties as a counterirritant. The action on nerve endings also induces a slight local analgesia...
Corticosteroids, such as hydrocortisone topical cream; see topical steroid Counterirritants, such as mint oil, menthol, or camphor Crotamiton (trade name Eurax)...
glauca. The stem prickles have been rubbed on the skin to act as a counterirritant to relieve pain and muscle cramps. The stems and leaves have also been...
to provide relief on the site of injury. Acetaminophen, opioids and counterirritants are common analgesics used in the therapy of arthritis. However, these...
descending modulation. DNIC forms the basis for the use of counterirritant to reduce pain. Counterirritant Counterstimulation Pain Le Bars D, Dickenson AH, Besson...
have drastically different pharmacology. Some act as local anesthetic counterirritants and, thereby, exert an antitussive (cough suppressing) effect. Many...
Thapsia villosa was used as a blister-producing agent (vesicant) or a counterirritant, similar to resin derived from Thapsia garganica. In Spain, the resin...
the use of electronic media, such as television or virtual reality. Counterirritant Lalkhen, Abdul-Ghaaliq (2022). An Anatomy of Pain: How the Body and...
Corticosteroids such as hydrocortisone topical cream, see topical steroid Counterirritants, such as mint oil, menthol, or camphor Local anesthetics such as lidocaine...
Moon, and Claus D. Buergelt. "The effects of injection of an iodine counterirritant into the patellar ligaments of ponies: Application to stifle lameness...
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