Antipruritics, abirritants,[1] or anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis) or stinging nettle. It can also be caused by chronic kidney disease and related conditions.[2]
Abirritants consist of a large group of drugs belonging to different classes with varying mechanisms to treat itch. They may work either directly or indirectly to relieve itch, and evidence on their effectiveness varies from one class to another.[3] Some alternative medicines are also used to treat itch.[4][5] Side effects of abirritants also vary depending on the class of the drug. Even before the emergence of modern evidence-based medicine, abirritants have already been used in many civilizations, but practices and choice of drugs may differ by culture.[6]
^"Antipruritic definition and meaning | Collins English Dictionary". www.collinsdictionary.com. Retrieved 2021-03-25.
^Butler, David F. (2020-12-11). "Pruritus and Systemic Disease: Background, Pathophysiology, Etiology". Medscape.
^Simonsen E, Komenda P, Lerner B, Askin N, Bohm C, Shaw J, et al. (November 2017). "Treatment of Uremic Pruritus: A Systematic Review". American Journal of Kidney Diseases. 70 (5): 638–655. doi:10.1053/j.ajkd.2017.05.018. PMID 28720208.
^Shi ZF, Song TB, Xie J, Yan YQ, Du YP (2017). "The Traditional Chinese Medicine and Relevant Treatment for the Efficacy and Safety of Atopic Dermatitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials". Evidence-Based Complementary and Alternative Medicine. 2017: 6026434. doi:10.1155/2017/6026434. PMC 5497608. PMID 28713436.
^Tabassum N, Hamdani M (January 2014). "Plants used to treat skin diseases". Pharmacognosy Reviews. 8 (15): 52–60. doi:10.4103/0973-7847.125531. PMC 3931201. PMID 24600196.
^Weisshaar E, Grüll V, König A, Schweinfurth D, Diepgen TL, Eckart WU (December 2009). "The symptom of itch in medical history: highlights through the centuries". International Journal of Dermatology. 48 (12): 1385–94. doi:10.1111/j.1365-4632.2009.04117.x. PMID 20415680. S2CID 28909284.
Antipruritics, abirritants, or anti-itch drugs, are medications that inhibit the itching (Latin: pruritus) often associated with sunburns, allergic reactions...
as a tartrate salt, is a phenothiazine derivative that is used as an antipruritic (it prevents itching from causes such as eczema or poison ivy, by acting...
is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). It is a prescription, lotion-based medicine that...
Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It has...
bottle of Benadryl (diphenhydramine) gel intended for use as a topical antipruritic. Type Antihistamine, allergy medication Inception 1946 (1946) Manufacturer...
Joglekar, M.B. Bhide J.H. Balwani. An experimental method for screening antipruritic agents. British Journal of Dermatology. Volume 75 Issue 3 p. 117. March...
Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. It is an analog of diphenhydramine. Bazex...
oil, leather treatment Saddle soap, leather cleaning and conditioning Antipruritic, as the oil is often an ingredient in insect bite-reliever sticks "Final...
medical use in 1960. Dimetindene is used orally and topically as an antipruritic. It is used topically to treat skin irritations, such as insect bites...
corticosteroid for topical dermatologic use, possessing anti-inflammatory, antipruritic, and vasoconstrictive properties. The prodrug alclometasone dipropionate...
Anusol plus is zinc sulfate monohydrate and pramoxine HCL, which is antipruritic (also found in Gold Bond). Current products have zinc sulfate monohydrate...
the brand name Pyribenzamine by Novartis, is a drug that is used as an antipruritic and first-generation antihistamine. It can be used in the treatment of...
site of application. They differ from the anesthetics, analgesics, and antipruritic agents, however, in that the pain relief they produce results from stimulation—rather...
Joglekar, M. B. Bhide J. H. Balwani. An experimental method for screening antipruritic agents. British Journal of Dermatology. Volume 75 Issue 3 Page 117 -...
is considered poisonous, it has beneficial uses as an antiparasitic, antipruritic, and haemostatic treatment. Hong Kong Flora and Vegetation Excoecaria...
Remitch; former developmental code names TRK-820, AC-820, MT-9938) is an antipruritic (anti-itch drug) that is marketed in Japan for the treatment of uremic...
Europe. Nutrition information is shown in the infobox on the right. Antipruritic "Rumex L.". Plants of the World Online. Royal Botanic Gardens, Kew. Retrieved...
ingredients include phenol 1.2% (providing antiseptic, locally analgesic and antipruritic effects) and chlorhexidine digluconate 0.25%. The Germoloids line of...
anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. During research and development, pramocaine hydrochloride stood out...
(or neohetramine) is an antihistamine and anticholinergic used as an antipruritic. Zolamine Arminio JJ, Sweet CC (December 1949). "The prophylaxis and...
generation H1 antagonist (antihistamine) and anticholinergic used as an antipruritic. In the 2020s, at least, it is rarely used in the first line relief of...
Non-chemical remedies include cooling, warming, soft stimulation. Topical antipruritics in the form of creams and sprays are often available over-the-counter...
an H1 antihistamine with anticholinergic properties. It is used as an antipruritic ointment. No oral use is known. Side effects are typical of an old (first-generation)...
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications...
Astemizole is a histamine H1-receptor antagonist. It has anticholinergic and antipruritic effects. Astemizole is rapidly absorbed from the gastrointestinal tract...
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