Cordia salicifolia, also called Cordia ecalyculata and chá de bugre, is a species of evergreen flowering tree in the borage family, Boraginaceae, that occurs mainly in Brazil and is used as a medicinal plant. Its red fruit, which resembles a coffee bean and contains caffeine, is roasted and brewed as a coffee substitute.
The leaves and fruit contain compounds such as caffeine, allantoin, allantoic acid, β-sitosterol, and spathulenol, as well as a significant amount of the electrolyte potassium.[1] The plant has been used as a diuretic, as an appetite suppressant, and to promote skin healing.[2][3] It shows activity against herpes simplex virus type 1 (HSV-1) in vitro.[4][5] It has also shown some usefulness as a snakebite antivenom.[6]
^Cite error: The named reference healing was invoked but never defined (see the help page).
^Fern, Ken (2019). Useful Tropical Plants Database.
^Menghini, Luigi; Epifano, Francesco; Leporini, Lidia; Pagiotti, Rita; Tirillini, Bruno (March 2008). "Phytochemical investigation on leaf extract of Cordia salicifolia cham". Journal of Medicinal Food. 11 (1): 193+. doi:10.1089/jmf.2007.583.
^Hayashi, K; Hayashi, T; Morita, N; Niwayama, S (October 1990). "Antiviral activity of an extract of Cordia salicifolia on herpes simplex virus type 1". Planta Med. 56 (5): 439–443. doi:10.1055/s-2006-961006. PMID 1963951.
^Caparroz-Assef, Silvana Martins (2005). "Toxicity studies of Cordia salicifolia extract = Estudo da toxidade do extrato de Cordia salicifolia". Acta Scientiarum - Health Sciences. 27 (1): 41–44. doi:10.4025/ACTASCIHEALTHSCI.V27I1.1439.
^Schezaro-Ramos, Raphael; Collaço, Rita C; Cogo, José C; Dal-Belo, Cháriston A; Rodrigues-Simioni, Léa; Rocha, Thalita; Randazzo-Moura, Priscila (July 2020). "Cordia salicifolia and Lafoensia pacari plant extracts against the local effects of Bothrops jararacussu and Philodryas olfersii snake venoms". J Venom Res. 10: 32–37. PMC 7512476. PMID 33024546.
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