Contact normalization is a process by which intercellular junctions mediate signals that allow normal cells to inhibit the transformed growth of neighboring tumor cells. Intimate junctional contact between tumor cells and normal cells is needed for this form of growth control. Contact normalization describes the ability of nontransformed cells to normalize the growth of neighboring cancer cells. This is a very widespread and powerful phenomenon. Tumor cells need to overcome this form of growth inhibition before they can become malignant or metastatic. Induction of a select set of genes has been associated with the ability of cancer cells to escape contact normalization. These include podoplanin (PDPN), vascular endothelial growth factor receptor 2/kinase insert domain receptor (VEGFR2/KDR), and transmembrane protein 163 (TMEM163) receptors.
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Contactnormalization is a process by which intercellular junctions mediate signals that allow normal cells to inhibit the transformed growth of neighboring...
The Abraham Accords are bilateral agreements on Arab–Israeli normalization signed between Israel and the United Arab Emirates and between Israel and Bahrain...
Digital contact tracing is a method of contact tracing relying on tracking systems, most often based on mobile devices, to determine contact between an...
thrusting the viewer into their current disposition, with its fear of contact, normalized violence and ancestral hardship." Solo exhibitions Wall Sits, Kunstverein...
corrosion occurs when two different metals have physical or electrical contact with each other and are immersed in a common electrolyte, or when the same...
Kangaroo mother care (KMC), which involves skin-to-skin contact (SSC), is an intervention to care for premature or low birth weight (LBW) infants. The...
eight women accused Biden of previous instances of inappropriate physical contact, such as embracing, touching or kissing. Biden had previously called himself...
dark or indoor conditions, but turn into sunglasses when they come into contact with ultraviolet light. Most over-the-counter sunglasses do not have corrective...
higher than the federal level. For certain federal or state government contacts, employers must pay the so-called prevailing wage as determined according...
overdose deaths continue to escalate, and children suffer the toxic normalization of transgenderism with drag queens and pornography invading their school...
Abraham Accord, which was the first normalization agreement between Israel and an Arab country since it normalized relations with Jordan in 1994. As part...
have been developed. Today the most used are the profiles with or without contact flats, while some other profiles, like disc springs with trapezoidal cross-section...
In psychology and media studies, the parasocial contact hypothesis is that positive portrayals of minority groups in mass media can reduce prejudice in...
selected. The free energy F serves two roles: first, it provides a normalization factor for the probability distribution (the probabilities, over the...
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