Tubulovillous adenoma (tubular component – left of image, villous component – right of image). H&E stain.
Specialty
Gastroenterology
Symptoms
Asymptomatic, rectal bleeding
Complications
Colorectal cancer
Diagnostic method
Colonoscopy
Treatment
Polypectomy
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma (colon cancer).[1][2][3] They often manifest as colorectal polyps.
^Hardcastle, J. D.; Armitage, N. C. (1984). "Early diagnosis of colorectal cancer: A review". Journal of the Royal Society of Medicine. 77 (8): 673–6. doi:10.1177/014107688407700812. PMC 1440108. PMID 6384511.
^Schofield, P. F.; Jones, D. J. (1992). "ABC of colorectal diseases. Colorectal neoplasia—I: Benign colonic tumours". BMJ (Clinical Research Ed.). 304 (6840): 1498–500. doi:10.1136/bmj.304.6840.1498. PMC 1882234. PMID 1319254.
^Srivastava, S; Verma, M; Henson, D. E. (2001). "Biomarkers for early detection of colon cancer". Clinical Cancer Research. 7 (5): 1118–26. PMID 11350874.
and 28 Related for: Colorectal adenoma information
The colorectaladenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma (colon cancer)...
hyperplastic polyp), pre-malignant (e.g. tubular adenoma) or malignant (e.g. colorectal adenocarcinoma). Colorectal polyps are not usually associated with symptoms...
An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs...
and colorectal cancer to progress. The polyp to cancer progression sequence is the classical model of colorectal cancer pathogenesis. In this adenoma-carcinoma...
in colorectaladenomas. Features that distinguish a hyperplastic polyp from a tubular colorectaladenoma are as follows: A sessile serrated adenoma or...
carcinoid Precancer – Tubular adenoma (left of image), a type of colonic polyp and a precursor of colorectal cancer. Normal colorectal mucosa is seen on the right...
rheumatoid arthritis. It may also be used to decrease the risk of colorectaladenomas in people with familial adenomatous polyposis. It is taken by mouth...
Colorectal surgery is a field in medicine dealing with disorders of the rectum, anus, and colon. The field is also known as proctology, but this term is...
synthesis enzyme, CYP7A1, influenced the effectiveness of UDCA in colorectaladenoma prevention in a large trial. Bile acids may be used in subcutaneous...
serrated adenoma is a premalignant type of polyp found in the colon, often in the distal colon (sigmoid, rectum). Traditional serrated adenomas are a type...
nonpolyposis colorectal cancer (Lynch syndrome). It is not the same as "adenoma sebaceum" by F. Balzer and P.E. Ménétrier (1885). The term "adenoma sebaceum"...
cancer: Molecular basis of colorectal cancer Cardiovascular risk associated with celecoxib in a clinical trial for colorectaladenoma prevention Dissecting...
gammopathy of unknown significance, or to certain lesions, such as colorectaladenoma (colon polyps), which have the potential to progress into cancer (see:...
(March 2005). "Cardiovascular events associated with rofecoxib in a colorectaladenoma chemoprevention trial". N. Engl. J. Med. 352 (11): 1092–102. doi:10...
failure Colorectal cancer Sleep apnea Thyroid nodules and thyroid cancer Hypogonadism Compression of the optic chiasm by the growth of pituitary adenoma leading...
(November 2013). "Dietary intake of vitamins A, C, and E and the risk of colorectaladenoma: a meta-analysis of observational studies". European Journal of Cancer...
increased BMI and risk of colorectaladenoma has been reported, as has a dose–response relationship between BMI and colorectaladenoma risk. Increased BMI also...
that k-Ras becomes activated and the polyp becomes a small, benign adenoma. The adenoma, lacking the "carcinoma" attached to the end of it, suggests that...
Mouse models of colorectal cancer and intestinal cancer are experimental systems in which mice are genetically manipulated, fed a modified diet, or challenged...
methylation status of hMLH1, hMSH2, and MGMT genes in colorectal cancer associated with adenoma-carcinoma sequence". Langenbecks Arch Surg. 396 (7): 1017–26...
Jakob (2009-05-01). "Heterocyclic aromatic amine intake increases colorectaladenoma risk: findings from a prospective European cohort study". The American...
a higher risk of colorectal cancer. In 1996, a case series revealed an association of the syndrome with cancer and serrated adenomas. Subsequently, other...
genetic alterations characteristic of the colorectaladenoma-carcinoma sequence does not occur between gastric adenoma and adenocarcinoma". J. Pathol. 176 (3):...
(March 2005). "Cardiovascular events associated with rofecoxib in a colorectaladenoma chemoprevention trial". The New England Journal of Medicine. 352 (11):...
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