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Choclo orthohantavirus information


Choclo orthohantavirus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Hantaviridae
Genus: Orthohantavirus
Species:
Choclo orthohantavirus

Choclo orthohantavirus (CHOV) is a single-stranded, negative-sense RNA zoonotic New World hantavirus. It was first isolated in 1999 in western Panama. The finding marked the first time Hantavirus pulmonary syndrome (HPS) was found in Central America.[1]

During this outbreak, a high seroprevalence was found among the general population, suggesting that this virus has an extremely low pathogenicity and causes sub-clinical to mild symptoms. This was confirmed in a study that infected hamsters with CHOV. All of the hamsters tested positive for CHOV, but none exhibited any symptoms.[2]

  1. ^ Nelson, R; Cañate, R; Pascale, JM; Dragoo, JW; Armien, B; Armien, AG; Koster, F (Sep 2010). "Confirmation of Choclo virus as the cause of hantavirus cardiopulmonary syndrome and high serum antibody prevalence in Panama". J Med Virol. 82 (9): 1586–93. doi:10.1002/jmv.21864. PMC 2927102. PMID 20648614.
  2. ^ Eyzaguirre, EJ; Milazzo, ML; Koster, FT; Fulhorst, CF (Apr 2008). "Choclo virus infection in the Syrian golden hamster". Am J Trop Med Hyg. 78 (4): 669–74. doi:10.4269/ajtmh.2008.78.669. PMC 2689364. PMID 18385367.

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