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Chloroacetamide information


Chloroacetamide
Names
Preferred IUPAC name
2-Chloroacetamide
Identifiers
CAS Number
  • 79-07-2 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:361034
ChemSpider
  • 6332
ECHA InfoCard 100.001.068 Edit this at Wikidata
EC Number
  • 201-174-2
PubChem CID
  • 6580
UNII
  • 2R97846T1L checkY
CompTox Dashboard (EPA)
  • DTXSID9041570 Edit this at Wikidata
InChI
  • InChI=1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)
    Key: VXIVSQZSERGHQP-UHFFFAOYSA-N
  • InChI=1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5)
    Key: VXIVSQZSERGHQP-UHFFFAOYAM
SMILES
  • ClCC(=O)N
Properties
Chemical formula
ClCH2CONH2
Molar mass 93.51 g·mol−1
Appearance Colorless crystals or white fine powder[1] (yellow if impure)
Odor Characteristic
Density 1.58 g/cm3 at 20 °C[1]
Melting point 120 °C (248 °F; 393 K)
Solubility in water
  • 52.5 g/l at 20 °C[1]
  • 90 g/L at 25 °C
Vapor pressure 0.07 hPa at 20 °C[1]
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Very toxic. It is suspected of reproductive toxicity and teratogenicity.
Ingestion hazards
Very toxic
Inhalation hazards
Very toxic
Eye hazards
Irritation
Skin hazards
Irritation
GHS labelling:
Pictograms
GHS06: ToxicGHS08: Health hazard
Signal word
Danger
Hazard statements
H301, H317, H361, H402
Precautionary statements
P201, P202, P261, P264, P270, P272, P273, P280, P301+P310+P330, P302+P352, P308+P313, P333+P313, P405, P501
Flash point 170 °C (338 °F; 443 K)
Lethal dose or concentration (LD, LC):
LD50 (median dose)
138 mg/kg (oral, rat)
>2000 mg/kg (skin, rat)
LC50 (median concentration)
19.8 mg/l, 96 h (Carassius auratus (goldfish))
Safety data sheet (SDS) [1]
Related compounds
Related compounds
  • Fluoroacetamide
  • Bromoacetamide
  • Iodoacetamide
  • Chloroacetic acid
  • Acetamide
  • Dichloroacetamide
  • N-Chlorosuccinimide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chloroacetamide (2-chloroacetamide) is a chlorinated organic compound with the molecular formula ClCH2CONH2. It is a colorless solid although older samples appear yellow. It has a characteristic odor and is readily soluble in water.[2] It has the structure Cl−CH2−C(=O)−NH2.

  1. ^ a b c d e https://www.sigmaaldrich.cn/CN/en/sds/mm/8.02412?userType=anonymous
  2. ^ 2-Chloroacetamide

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Chloroacetamide (2-chloroacetamide) is a chlorinated organic compound with the molecular formula ClCH2CONH2. It is a colorless solid although older samples...

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James Maybrick

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the ink contained chloroacetamide, a preservative, in an effort to definitively date the ink. According to one source, chloroacetamide was introduced into...

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Amide

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dimethylformamide (H−C(=O)−N(−CH3)2). Some uncommon examples of amides are N-chloroacetamide (H3C−C(=O)−NH−Cl) and chloroformamide (Cl−C(=O)−NH2). Amides are qualified...

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Dimethenamid

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Dimethenamid is a widely used herbicide belonging to the chloroacetamide class (group 15). Group 15 herbicides inhibit synthesis of certain long-chain...

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Benzydamine

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3-dimethylaminopropyl chloride gives benzydamine. Alternatively, use of chloroacetamide in the alkylation step followed by acid hydrolysis produces bendazac...

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Chloroacetonitrile

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replacement of one H with Cl. In practice, it is produced by dehydration of chloroacetamide. The compound is an alkylating agent, and as such is handled cautiously...

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Cyanoacetamide

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synthesis followed by Fischer esterification and ester aminolysis. Chloroacetamide Ethyl chloroacetate Ibrahim, F.; Sharaf El-Din, M. K.; Eid, M.; Wahba...

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Iodoacetamide

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MSDS 2 Related compounds Related compounds Acetamide Fluoroacetamide Chloroacetamide Bromoacetamide Iodoacetic acid Except where otherwise noted, data are...

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Bendazac

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pain. Principal action is inhibition of protein denaturation. Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac...

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species name comes from Latin vorans (devouring) and the herbicide chloroacetamide, referring to the type of herbicide waterwater from which the species...

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List of long species names

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chloroacetimidivorans Chen et al. 2014 - family Sphingomonadaceae. A Gram-negative, chloroacetamide-degrading and non-spore-forming bacterium which was isolated from activated...

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will. It has also been alleged that the ink contains the preservative chloroacetamide and that this was not commercially used in ink until 1972, although...

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Novosphingobium chloroacetimidivorans is a Gram-negative, chloroacetamide-degrading and non-spore-forming bacterium from the genus Novosphingobium which...

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Darzens reaction

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Frazier, H. W. (June 1963). "The Darzens Condensation. II. Reaction of Chloroacetamides with Aromatic Aldehydes". Journal of Organic Chemistry. 28 (6): 1514–1521...

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Fluoroacetamide

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Roseomonas

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ZG, He Q, He J, Gu JG. Roseomonas chloroacetimidivorans sp. nov., a chloroacetamide herbicide-degrading bacterium isolated from activated sludge. Antonie...

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Roseomonas eburnea

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ZG, He Q, He J, Gu JG. Roseomonas chloroacetimidivorans sp. nov., a chloroacetamide herbicide-degrading bacterium isolated from activated sludge. Antonie...

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