Centre for Gene Regulation and Expression information
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The Centre for Gene Regulation and Expression, located within the School of Life Sciences, University of Dundee, is a research facility working in the field of gene expression and chromosome biology. Previously part of the Dundee Biocentre and receiving significant Wellcome Trust funding from 1995 onwards, it was awarded Wellcome Trust Centre status in 2008. Professor Tom Owen-Hughes is the centre's director.
The centre aims to enhance our understanding of how genes are regulated at both the single cell and whole organism level. Researchers use a wide range of advanced techniques, including live cell fluorescent imaging and mass spectrometry-based proteomics, to explore the functions of key proteins and molecular mechanisms in cell biology.
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and post-translational modification of a protein. Regulation of geneexpression gives control over the timing, location, and amount of a given gene product...
MRC-Phosphorylation and Ubiquitylation Unit, and in 2015 joined The CentreforGeneRegulationandExpression. During her postdoctoral studies at Dartmouth College...
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Life Sciences's CentreforGeneRegulationandExpression. In Dundee he was funded by Cancer Research UK (CRUK) Career Development and Wellcome Trust Senior...
identification and characterization of genomic regions associated with generegulation. This is connected to research on Chromatin andGeneExpression, as well...
recognised for publishing the Booker Prizewinner Life of Pi. Canongate was named the British Book Awards Publisher of the Year in 2003 and 2009. Canongate...
interference mapping. The Xist RNA gene lies within the X-inactivation centre (XIC), which plays a major role in Xist expressionand X-inactivation. The XIC is...
Infirmary for their famed research and clinical investigation into circulatory diseases and cardiology. Maryfield closed in stages between 1974 and 1976 following...
in regulation of geneexpression. The group analyses the biology of micro-RNA's using computational methods and develop tools that are useful for experimental...
membrane. This allows for the temporal regulation of geneexpression through the sequestration of the RNA in the nucleus, and allows for selective transport...
are acetylated and deacetylated as part of generegulation. Histone acetylation and deacetylation are essential parts of generegulation. These reactions...
transcripts by competing for shared microRNAs (miRNAs). Models for ceRNA regulation describe how changes in the expression of one or multiple miRNA targets...
recombinant protein expressionand purification, stable cell line development, custom monoclonal and polyclonal antibody development and various proteomics...
clinical research centre; and in Kirkcaldy, Fife, containing part of its School of Health Sciences. The annual income of the institution for 2022–23 was £325...
leading centresfor small and medium enterprise development and enterprise. He then moved to the University of Lincoln in 2002, where he worked for 10 years...
"Novel insights into geneexpressionregulation during meiosis revealed by translation elongation dynamics". npj Systems Biology and Applications. 5 (1):...
accounts for both social determination and social change.[citation needed] The second concerns the construction of social categories through language and action...
in 1974, DRI remained as the principal emergency centrefor Dundee, with the expectation that this, and other functions it retained, would be moved at a...
(See below for a more detailed discussion). One study looked at the pattern of KNOX geneexpression in A. thaliana, that has simple leaves and Cardamine...
basis of drug regulation of geneexpression Nestler EJ, Barrot M, Self DW (September 2001). "DeltaFosB: a sustained molecular switch for addiction". Proceedings...
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