Cecropins are antimicrobial peptides.[1][2] They were first isolated from the hemolymph of Hyalophora cecropia, whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes.
Cecropins[3][4][5] constitute a main part of the innate immune system of insects. Cecropins are small proteins anywhere from 31 - 37 amino acids long and are active against both gram-positive and gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names, such as bactericidin, lepidopterin, and sarcotoxin. All of these peptides are structurally related.
^Cecropins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
^Lauwers A, Twyffels L, Soin R, Wauquier C, Kruys V, Gueydan C (March 2009). "Post-transcriptional Regulation of Genes Encoding Anti-microbial Peptides in Drosophila". The Journal of Biological Chemistry. 284 (13): 8973–83. doi:10.1074/jbc.M806778200. PMC 2659254. PMID 19176529.
^Boman HG, Hultmark D (1987). "Cell-free immunity in insects". Annual Review of Microbiology. 41: 103–26. doi:10.1146/annurev.mi.41.100187.000535. PMID 3318666.
^Boman HG, Faye I, Gudmundsson GH, Lee JY, Lidholm DA (October 1991). "Cell-free immunity in Cecropia. A model system for antibacterial proteins". European Journal of Biochemistry. 201 (1): 23–31. doi:10.1111/j.1432-1033.1991.tb16252.x. PMID 1915368.
Cecropins are antimicrobial peptides. They were first isolated from the hemolymph of Hyalophora cecropia, whence the term cecropin was derived. Cecropins...
abdomen to permit extraction of detectable amounts from a single specimen. Cecropin, a major protein involved in the humoral immunity of most insects, was...
cecropins (e.g. cecropin A, and cecropin B) have anticancer properties and are called anticancer peptides (ACPs).: 3 Hybrid ACPs based on Cecropin A...
bloodstream where they perform their signaling functions. Magainin family Cecropin family Cathelicidin family Defensin family Substance P Kassinin Neurokinin...
Agriculture is a significant sector in California's economy, producing nearly US$50 billion in revenue in 2018[update]. There are more than 400 commodity...
cruzi. The strategy was to engineer R. rhodnii to express proteins such as Cecropin A that are toxic to T. cruzi or that block the transmission of T. cruzi...
is essential for activation of antimicrobial peptides, defensins, and cecropins that help to inhibit virus proliferation. Conversely, certain strains...
species of insect produce antimicrobial peptides known as defensins and cecropins. In invertebrates, PRRs trigger proteolytic cascades that degrade proteins...
to kill pathogenic bacteria and helminth parasites. Among the toxins, cecropin was identified as the pain-causing chemical. It was experimented with bacteria...
potential use by the competent cells. The insect antimicrobial peptide cecropin A can destroy planktonic and sessile biofilm-forming uropathogenic E. coli...
cysteine proteinase inhibitor gene from taro. A chemically synthesised cecropin B gene, usually found in the giant silk moth (Hyalophora cecropia), has...
that drosomycin, alongside other antimicrobial peptides (AMPs) such as cecropins, diptericin, drosocin, metchnikowin and attacin, serves as a first line...
infection have been analysed based on injection by Escherichia coli D31. Cecropin B and D, hemolin, attacin and lysozyme were detected in the hemolymph....
helical structure. Structural similarities to the antimicrobial peptide cecropin A from Hyalophora cecropia suggest that it may function in a similar manner...
after exposure to Aeromonas bacteria and Grass carp hemorrhage virus. Cecropin has been used in channel catfish to enhance their protection against several...
peptide genes of Drosophila, particularly: Diptericin, Attacin, Drosocin, Cecropin, and Defensin. The Imd pathway regulates hundreds of genes after infection...
DCH; et al. (Nov 2017). "Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle". PLOS ONE. 12...
identifying number or letter. However many Sarcotoxins are homologues of Cecropins or Attacins, and are not unique to Sarcophaga flies. Iwai, H.; Nakajima...
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