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Infobox references
Chemical compound
Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections.[1][2][3] It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis (blackhead disease).[4][5]
Carbarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry and/or swine, along with nitarsone, arsanilic acid, and roxarsone.[6] In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place.[7] In 2015 FDA withdrew the approval of using nitarsone in animal feeds. The ban came into effect at the end of 2015.[8]
^SASAKI T, YOKAGAWA M, WYKOFF DE, RITICHIE LS (1956). "Asymptomatic amebiasis; treatment with atabrine in combination with carbarsone or chiniofon". United States Armed Forces Medical Journal. 7 (3): 363–8. PMID 13299463.
^RADKE RA (1955). "Ameboma of the intestine: an analysis of the disease as presented in 78 collected and 41 previously unreported cases". Ann. Intern. Med. 43 (5): 1048–66. doi:10.7326/0003-4819-43-5-1048. PMID 13268997.
^HOEKENGA MT (1 July 1951). "A comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis". Am. J. Trop. Med. Hyg. 31 (4): 423–5. doi:10.4269/ajtmh.1951.s1-31.423. PMID 14857246.
^McDougald LR (1979). "Efficacy and compatibility of amprolium and carbarsone against Coccidiosis and blackhead in turkeys". Poult. Sci. 58 (1): 76–80. doi:10.3382/ps.0580076. PMID 572970.
^Worden AN, Wood EC (1973). "The effect of Carbarsone (33.6 per cent w-v p-ureidobenzene arsonic acid) on bodyweight gain, food conversion and tissue arsenic levels of turkey poults". J. Sci. Food Agric. 24 (1): 35–41. doi:10.1002/jsfa.2740240107. PMID 4696593.
^U.S. Food and Drug Administration (June 8, 2011). "Questions and Answers Regarding 3-Nitro (Roxarsone)".
^U.S. Food and Drug Administration (September 20, 2011). "FDA Response to Citizen Petition on Arsenic-based Animal Drugs".
^U.S. Food and Drug Administration (April 1, 2015). "FDA Announces Pending Withdrawal of Approval of Nitarsone".
Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. It was available for amebiasis in...
Some arsenical compounds are shown to treat the trophozoite stage, like carbarsone. Other compounds used to treat large populations of E. coli include diloxanide...
arsenical food-animal drugs—along with roxarsone, arsanilic acid, and carbarsone—approved by the U.S. Food and Drug Administration for use in feeding poultry...
for use in poultry and swine, along with nitarsone, arsanilic acid, and carbarsone. In September 2013, the FDA announced that Zoetis and Fleming Laboratories...
arsanilic acid was among four arsenical veterinary drugs, along with carbarsone, nitarsone, roxarsone, approved by the U.S. Food and Drug Administration...
antiprotozoals, were reported to be effective against the infection. Carbarsone was available as an anti-infective compound in the United States as late...