negative regulation of cell population proliferation
protein ubiquitination
viral process
ERBB2 signaling pathway
calcium ion transmembrane transport
cellular response to DNA damage stimulus
post-translational protein modification
G1/S transition of mitotic cell cycle
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
8065
75717
Ensembl
ENSG00000166266
ENSMUSG00000032030
UniProt
Q93034
Q9D5V5
RefSeq (mRNA)
NM_003478
NM_001161618 NM_027807
RefSeq (protein)
NP_003469
NP_001155090 NP_082083
Location (UCSC)
Chr 11: 108.01 – 108.11 Mb
Chr 9: 53.53 – 53.58 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Cullin-5 is a protein that in humans is encoded by the CUL5 gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000166266 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000032030 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM (Aug 1996). "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family". Cell. 85 (6): 829–39. doi:10.1016/S0092-8674(00)81267-2. PMID 8681378. S2CID 15805562.
^Byrd PJ, Stankovic T, McConville CM, Smith AD, Cooper PR, Taylor AM (May 1997). "Identification and analysis of expression of human VACM-1, a cullin gene family member located on chromosome 11q22-23". Genome Res. 7 (1): 71–5. doi:10.1101/gr.7.1.71. PMID 9037604.
Cullin-5 is a protein that in humans is encoded by the CUL5 gene. The mammalian gene product was originally discovered by expression cloning, due to the...
(Elongin C - CUL2 - SOCS-box) CUL3, part of CUL3-BTB complex CUL4A CUL4B CUL5 CUL7 CUL9, also known as PARC There is also a more distant member called...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53...
binds to A3G as well as the cellular Cullin5 E3 Ubiquitin Ligase (ELOB-ELOC-CUL5) and a CBFB cofactor so that the ligase can be hijacked to tag A3G for degradation...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J. Biol. Chem. 276 (32): 29748–53...
Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase". J Biol Chem. 276 (32): 29748–53...