CRYM information

CRYM
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I99
Identifiers
Aliases	CRYM, DFNA40, THBP, crystallin mu
External IDs	OMIM: 123740; MGI: 102675; HomoloGene: 1424; GeneCards: CRYM; OMA:CRYM - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	21,303,083 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	119,801,334 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; frontal pole; ; paraflocculus of cerebellum; ; right hemisphere of cerebellum; ; Brodmann area 10; ; orbitofrontal cortex; ; apex of heart; ; nucleus accumbens; ; Brodmann area 9; ; right frontal lobe;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; hippocampus proper; ; olfactory tubercle; ; nucleus accumbens; ; subiculum; ; lip; ; dorsal striatum; ; Region I of hippocampus proper; ; superior frontal gyrus; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; hormone binding; protein binding; protein homodimerization activity; transcription corepressor activity; NADP binding; thyroid hormone binding; thiomorpholine-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor;
Cellular component	cytoplasm; extracellular exosome; mitochondrion; nucleus; peroxisomal matrix; cytosol;
Biological process	thyroid hormone transport; negative regulation of transcription by RNA polymerase II; hearing; lysine catabolic process; thyroid hormone metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1428
	12971
	ENSG00000103316
	ENSMUSG00000030905
	Q14894
	O54983
	NM_001014444; NM_001888; NM_001376256
	NM_016669
	NP_001879; NP_001363185
	NP_057878
	Wikidata
View/Edit Human	View/Edit Mouse

Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000103316 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030905 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chen H, Phillips HA, Callen DF, Kim RY, Wistow GJ, Antonarakis SE (Feb 1993). "Localization of the human gene for mu-crystallin to chromosome 16p". Genomics. 14 (4): 1115–6. doi:10.1016/S0888-7543(05)80143-0. PMID 1478656.
^ "Entrez Gene: CRYM crystallin, mu".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000103316 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030905 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1478656-5] Chen H, Phillips HA, Callen DF, Kim RY, Wistow GJ, Antonarakis SE (Feb 1993). "Localization of the human gene for mu-crystallin to chromosome 16p". Genomics. 14 (4): 1115–6. doi:10.1016/S0888-7543(05)80143-0. PMID 1478656.

[entrez-6] "Entrez Gene: CRYM crystallin, mu".

CRYM information

and 25 Related for: CRYM information

CRYM

Crystallin

Cantharellus cibarius

Cantharellus ferruginascens

Cantharellus alborufescens

Cantharellus

Thyroid hormones

Bonomyces

Coelomycetes

Largest fungal fruit bodies

Cantharellus velutinus

Clathrus roseovolvatus

Climacocystis borealis

Pipecolic acid

Clathrus

Diplodia allocellula

Dothiorella dulcispinae

Hericium bharengense

Boidinella

Hericium

Cantharellus iuventateviridis

Hypsizygus ulmarius

Podoserpula miranda

Hyphodermella

Spencermartinsia pretoriensis