CHST1 information

CHST1
Identifiers
Aliases	CHST1, C6ST, GST-1, KS6ST, KSGal6ST, KSST, carbohydrate sulfotransferase 1
External IDs	OMIM: 603797; MGI: 1924219; HomoloGene: 2711; GeneCards: CHST1; OMA:CHST1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	45,665,622 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	92,445,595 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 10; ; middle frontal gyrus; ; parietal lobe; ; amygdala; ; postcentral gyrus; ; orbitofrontal cortex; ; dorsolateral prefrontal cortex; ; caudate nucleus; ; putamen;
	Top expressed in
	lacrimal gland; ; molar; ; habenula; ; olfactory tubercle; ; subiculum; ; temporal lobe; ; prefrontal cortex; ; nucleus accumbens; ; primary motor cortex; ; piriform cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; keratan sulfotransferase activity;
Cellular component	Golgi membrane; Golgi apparatus; membrane; integral component of membrane; trans-Golgi network;
Biological process	sulfur compound metabolic process; galactose metabolic process; inflammatory response; keratan sulfate biosynthetic process; polysaccharide metabolic process; keratan sulfate metabolic process; carbohydrate metabolic process; N-acetylglucosamine metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	8534
	76969
	ENSG00000175264
	ENSMUSG00000027221
	O43916
	Q9EQC0
	NM_003654
	NM_023850; NM_001356552; NM_001356553
	NP_003645
	NP_076339; NP_001343481; NP_001343482
	Wikidata
View/Edit Human	View/Edit Mouse

Carbohydrate sulfotransferase 1 is an enzyme that in humans is encoded by the CHST1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175264 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027221 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O (Jan 1998). "Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase". J Biol Chem. 272 (51): 32321–8. doi:10.1074/jbc.272.51.32321. PMID 9405439.
^ Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ (Aug 1998). "Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization". Biochim Biophys Acta. 1407 (1): 92–7. doi:10.1016/s0925-4439(98)00028-3. PMID 9639683.
^ "Entrez Gene: CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175264 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027221 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9405439-5] Fukuta M, Inazawa J, Torii T, Tsuzuki K, Shimada E, Habuchi O (Jan 1998). "Molecular cloning and characterization of human keratan sulfate Gal-6-sulfotransferase". J Biol Chem. 272 (51): 32321–8. doi:10.1074/jbc.272.51.32321. PMID 9405439.

[pmid9639683-6] Mazany KD, Peng T, Watson CE, Tabas I, Williams KJ (Aug 1998). "Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization". Biochim Biophys Acta. 1407 (1): 92–7. doi:10.1016/s0925-4439(98)00028-3. PMID 9639683.

[entrez-7] "Entrez Gene: CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1".

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