dentate gyrus of hippocampal formation granule cell
intestinal villus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
protein homodimerization activity
protein domain specific binding
zinc ion binding
protein binding
identical protein binding
metallopeptidase activity
Cellular component
cytoplasm
endosome
membrane
microtubule organizing center
condensed nuclear chromosome
early endosome
endosome membrane
extracellular exosome
endomembrane system
nucleus
nuclear matrix
ESCRT III complex
multivesicular body
Biological process
carbon catabolite repression of transcription by glucose
regulation of centrosome duplication
regulation of transcription, DNA-templated
viral budding via host ESCRT complex
nucleus organization
multivesicular body assembly
regulation of mitotic spindle assembly
transcription, DNA-templated
cell division
protein transport
cell cycle
septum digestion after cytokinesis
mitotic metaphase plate congression
negative regulation of transcription, DNA-templated
vacuolar transport
ESCRT III complex disassembly
proteolysis
mitotic chromosome condensation
vesicle-mediated transport
transport
endosome transport via multivesicular body sorting pathway
late endosome to vacuole transport
negative regulation of cell cycle
midbody abscission
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
5119
234852
Ensembl
ENSG00000131165
ENSMUSG00000000743
UniProt
Q9HD42
Q921W0
RefSeq (mRNA)
NM_001083314 NM_002768
NM_145606
RefSeq (protein)
NP_001076783 NP_002759
NP_663581
Location (UCSC)
Chr 16: 89.64 – 89.66 Mb
Chr 8: 123.93 – 123.94 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Charged multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000131165 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000000743 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Howard TL, Stauffer DR, Degnin CR, Hollenberg SM (July 2001). "CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins". Journal of Cell Science. 114 (Pt 13): 2395–404. doi:10.1242/jcs.114.13.2395. PMID 11559748.
^Stauffer DR, Howard TL, Nyun T, Hollenberg SM (July 2001). "CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression". Journal of Cell Science. 114 (Pt 13): 2383–93. doi:10.1242/jcs.114.13.2383. PMID 11559747.
multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene. This gene encodes a member of the CHMP/Chmp family of proteins which...
Charged multivesicular body protein may refer to: CHMP1A CHMP1B CHMP2A CHMP2B CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CHMP (disambiguation) This disambiguation...
Charged multivesicular body protein (disambiguation) also known as CHMP CHMP1A CHMP1B CHMP2A CHMP2B CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 This disambiguation...
the other resides on chromosome 18. VPS4A has been shown to interact with CHMP1A. GRCh38: Ensembl release 89: ENSG00000132612 – Ensembl, May 2017 GRCm38:...
both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression...
Global Information
