CFHR5 nephropathy information

CFHR5 nephropathy
CFHR5 nephropathy
Other names	Troodos nephropathy
Specialty	Nephrology

Complement factor H-related protein 5 (CFHR5) nephropathy is a form of inherited kidney disease which is endemic in Cyprus and is caused by a mutation in the gene CFHR5.^[1] It is thought to affect up to 1:6000 Cypriots but has not been reported in anybody who is not of Cypriot descent.

^ Gale DP, de Jorge EG, et al. (26 August 2010). "Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis". Lancet. 376 (9743): 794–801. doi:10.1016/S0140-6736(10)60670-8. PMC 2935536. PMID 20800271.

[CFHR5N-1] Gale DP, de Jorge EG, et al. (26 August 2010). "Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis". Lancet. 376 (9743): 794–801. doi:10.1016/S0140-6736(10)60670-8. PMC 2935536. PMID 20800271.