C20orf27 information

C20orf27
Identifiers
Aliases	C20orf27, chromosome 20 open reading frame 27
External IDs	MGI: 1914576; HomoloGene: 41660; GeneCards: C20orf27; OMA:C20orf27 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	3,767,781 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	131,002,001 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; caudate nucleus; ; putamen; ; muscle layer of sigmoid colon; ; granulocyte; ; right ovary; ; left uterine tube; ; left ovary; ; decidua; ; monocyte;
	Top expressed in
	seminiferous tubule; ; supraoptic nucleus; ; brown adipose tissue; ; dorsomedial hypothalamic nucleus; ; somite; ; dorsal tegmental nucleus; ; olfactory tubercle; ; superior frontal gyrus; ; globus pallidus; ; nucleus accumbens;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	molecular function; protein binding;
Cellular component	cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	54976
	67326
	ENSG00000101220
	ENSMUSG00000027327
	Q9GZN8
	Q9D1K7
	NM_001039140; NM_001258429; NM_001258430; NM_017874
	NM_026091; NM_001311138; NM_001361375
	NP_001034229; NP_001245358; NP_001245359
	NP_001298067; NP_080367; NP_001348304
	Wikidata
View/Edit Human	View/Edit Mouse

UPF0687 protein C20orf27 is a protein that in humans is encoded by the C20orf27 gene.^[5]^[6] It is expressed in the majority of the human tissues. One study on this protein revealed its role in regulating cell cycle, apoptosis, and tumorigenesis via promoting the activation of NFĸB pathway.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101220 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027327 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, et al. (Jan 2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
^ "Entrez Gene: C20orf27 chromosome 20 open reading frame 27".
^ Gao J, Wang Y, Zhang W, Zhang J, Lu S, Meng K, et al. (February 2020). "C20orf27 Promotes Cell Growth and Proliferation of Colorectal Cancer via the TGFβR-TAK1-NFĸB Pathway". Cancers. 12 (2): 336. doi:10.3390/cancers12020336. PMC 7072304. PMID 32024300.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000101220 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027327 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11780052-5] Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, et al. (Jan 2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.

[entrez-6] "Entrez Gene: C20orf27 chromosome 20 open reading frame 27".

[7] Gao J, Wang Y, Zhang W, Zhang J, Lu S, Meng K, et al. (February 2020). "C20orf27 Promotes Cell Growth and Proliferation of Colorectal Cancer via the TGFβR-TAK1-NFĸB Pathway". Cancers. 12 (2): 336. doi:10.3390/cancers12020336. PMC 7072304. PMID 32024300.

C20orf27 information

and 3 Related for: C20orf27 information

C20orf27

Stress granule

Chromosome 20