Brompton cocktail, sometimes called Brompton mixture or Brompton's cocktail, was an elixir meant for use as a pain suppressant dosed for prophylaxis. Made from morphine or diacetylmorphine (heroin), cocaine, highly-pure ethyl alcohol (some recipes specify gin), and sometimes with chlorpromazine (Thorazine) to counteract nausea, it was given to terminally-ill individuals (especially cancer patients) to relieve pain and promote sociability near death. A common formulation included "a variable amount of morphine, 10 mg of cocaine, 2.5 mL of 98% ethyl alcohol, 5 mL of syrup BP and a variable amount of chloroform water."[1] Brompton's cocktail was given most in the mid twentieth century.[2] It is now considered obsolete.[3]
In popular culture it also came to be associated with medical euthanasia. According to legend (and perhaps in fact) doctors would provide a large dose to terminally ill patients who wished to die.[2][4]
^Melzak, R., B.M. Mount, and J.M. Gordon. "The Brompton mixture versus morphine solution given orally: effects on pain." The RVH Manual on Palliative/Hospice Care: A Resource Book. ed. Ajemian, Ina & Balfour M. Mount. Palliative Care Service: Royal Victoria Hospital, Montreal, Quebec. 1980. p. 172.
^ abCite error: The named reference :0 was invoked but never defined (see the help page).
^Brompton's Cocktail, Hospice Education Institute
^"Terry Pratchett" (1 February 2010). "My case for a euthanasia tribunal". The Guardian. Retrieved 29 August 2023.
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