3'-phosphoadenosine 5'-phosphosulfate metabolic process
steroid metabolic process
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6822
434121
Ensembl
ENSG00000105398
ENSMUSG00000074377
UniProt
Q06520
n/a
RefSeq (mRNA)
NM_003167
NM_001101534
RefSeq (protein)
NP_003158
n/a
Location (UCSC)
Chr 19: 47.87 – 47.89 Mb
Chr 7: 13.64 – 13.72 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Bile salt sulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by the SULT2A1 gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000105398 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000074377 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Bilesaltsulfotransferase also known as hydroxysteroid sulfotransferase (HST) or sulfotransferase 2A1 (ST2A1) is an enzyme that in humans is encoded by...
that is widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total...
enzymes such as CYP1A1 and CYP3A4 and via conjugation by estrogen sulfotransferases (sulfation) and UDP-glucuronyltransferases (glucuronidation). In addition...
DHEA-S is formed by sulfation of DHEA at the C3β position via the sulfotransferase enzymes SULT2A1 and to a lesser extent SULT1E1. Whereas DHEA is derived...
into its active metabolite prasterone sulfate (DHEA-S) by steroid sulfotransferase (specifically SULT1E1 and SULT2A1), which in turn can be converted...
17β-hydroxysteroid dehydrogenase 2 (converts estradiol into estrone) and estrone sulfotransferase (converts estrone into estrone sulfate). The antiestrogenic effects...