Organelle-like structure in bacteria with a protein shell containing enzymes
The structure of the Bacterial Microcompartment shell. The first structure of a BMC shell, determined by X-ray crystallography and cryo-electron microscopy,[1] contains representatives of each of the shell protein types: BMC-P, BMC-H and BMC-T, in both its trimer (upper right) and dimer of trimer (lower right), forms. [Image: Todd Yeates]
Bacterial microcompartments (BMCs) are organelle-like structures found in bacteria. They consist of a protein shell that encloses enzymes and other proteins. BMCs are typically about 40–200 nanometers in diameter and are made entirely of proteins.[2][3][4][5][6][7][8][9][10][11][12][13] The shell functions like a membrane, as it is selectively permeable.[4][6][8][14][15] Other protein-based compartments found in bacteria and archaea include encapsulin nanocompartments[16] and gas vesicles.[17]
^Sutter, Markus; Greber, Basil; Aussignargues, Clement; Kerfeld, Cheryl A. (2017-06-23). "Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell". Science. 356 (6344): 1293–1297. Bibcode:2017Sci...356.1293S. doi:10.1126/science.aan3289. PMC 5873307. PMID 28642439.
^Sutter, Markus; Melnicki, Matthew R.; Schulz, Frederik; Woyke, Tanja; Kerfeld, Cheryl A. (December 2021). "A catalog of the diversity and ubiquity of bacterial microcompartments". Nature Communications. 12 (1): 3809. Bibcode:2021NatCo..12.3809S. doi:10.1038/s41467-021-24126-4. ISSN 2041-1723. PMC 8217296. PMID 34155212.
^Cite error: The named reference ChengLiu2008 was invoked but never defined (see the help page).
^ abCite error: The named reference Kerfeld2005 was invoked but never defined (see the help page).
^Cite error: The named reference YeatesKerfeld2008 was invoked but never defined (see the help page).
^ abCite error: The named reference KerfeldErbilgin2015 was invoked but never defined (see the help page).
^Cite error: The named reference Cannon2001 was invoked but never defined (see the help page).
^ abCite error: The named reference KerfeldHeinhorst2010 was invoked but never defined (see the help page).
^Cite error: The named reference Yeates2010 was invoked but never defined (see the help page).
^Heinhorst, Sabine; Cannon, Gordon C. (2020), Jendrossek, Dieter (ed.), "Bacterial Microcompartments", Bacterial Organelles and Organelle-like Inclusions, Microbiology Monographs, vol. 34, Cham: Springer International Publishing, pp. 125–147, doi:10.1007/978-3-030-60173-7_6, ISBN 978-3-030-60172-0, S2CID 240735306, retrieved 2021-09-17
^Kennedy, Nolan W; Mills, Carolyn E; Nichols, Taylor M; Abrahamson, Charlotte H; Tullman-Ercek, Danielle (October 2021). "Bacterial microcompartments: tiny organelles with big potential". Current Opinion in Microbiology. 63: 36–42. doi:10.1016/j.mib.2021.05.010. PMID 34126434.
^Axen, Seth D.; Erbilgin, Onur; Kerfeld, Cheryl A. (2014-10-23). Tanaka, Mark M. (ed.). "A Taxonomy of Bacterial Microcompartment Loci Constructed by a Novel Scoring Method". PLOS Computational Biology. 10 (10): e1003898. Bibcode:2014PLSCB..10E3898A. doi:10.1371/journal.pcbi.1003898. ISSN 1553-7358. PMC 4207490. PMID 25340524.
^Mills, C. E.; Waltmann, C.; Archer, A.G.; Kennedy, N.W.; Abrahamson, C.H.; Jackson, A.D.; Roth, E.W.; Shirman, S.; Jewett, N.M.; Mangan, N.M.; Olvera de la Cruz, M.; Tullman-Ercek, D. (2022). "Vertex protein PduN tunes encapsulated pathway performance by dictating bacterial metabolosome morphology". Nature Communications. 13 (3746): 3746. doi:10.1038/s41467-022-31279-3. PMC 9243111. PMID 35768404.
^Cite error: The named reference Yeates2011 was invoked but never defined (see the help page).
^Cite error: The named reference KinneyAxen2011 was invoked but never defined (see the help page).
^Cite error: The named reference SutterBoehringer2008 was invoked but never defined (see the help page).
^Cite error: The named reference Pfeifer2012 was invoked but never defined (see the help page).
and 19 Related for: Bacterial microcompartment information
Bacterialmicrocompartments (BMCs) are organelle-like structures found in bacteria. They consist of a protein shell that encloses enzymes and other proteins...
compartmentalize bacterial metabolism, a function performed by the membrane-bound organelles in eukaryotes. Carboxysomes are bacterialmicrocompartments found in...
possess eukaryotic organelles, some do contain protein-shelled bacterialmicrocompartments, which are thought to act as primitive prokaryotic organelles;...
"Protein-based organelles in bacteria: carboxysomes and related microcompartments". Nature Reviews. Microbiology. 6 (9): 681–91. doi:10.1038/nrmicro1913...
Carboxysomes are bacterialmicrocompartments (BMCs) consisting of polyhedral protein shells filled with the enzymes ribulose-1,5-bisphosphate carboxylase/oxygenase...
its sole source of carbon and energy. The organism contains a bacterialmicrocompartment capable of processing propanediol. C. freundii creates a positive...
within the cytoplasm except for an outer cell membrane, but bacterialmicrocompartments, which are thought to be quasi-organelles enclosed in protein...
proteolytic cavity. Another large class of protein compartments are bacterialmicrocompartments, which are made of a protein shell that encapsulates various...
Bacterial phyla constitute the major lineages of the domain Bacteria. While the exact definition of a bacterial phylum is debated, a popular definition...
cellular functions, including cell division, cell elongation or bacterialmicrocompartment segregation are governed by the prokaryotic cytoskeleton. Cyanobacteria...
more specific strategies is the widespread prevalence of the bacterialmicrocompartments known as carboxysomes, which co-operate with active transporters...
In molecular biology the BacterialMicrocompartment (BMC) domain is a protein domain found in a variety of shell proteins, including CsoS1A, CsoS1B and...
closed membranes with non-homogeneous elastic properties such as bacterialmicrocompartments, including carboxysomes, via a mechanism that explains observed...
elements of poribacterial subcellular compartmentation: Firstly, Bacterialmicrocompartments, atypically localized at the cell membrane. Secondly, spherical...
S2CID 646883. van Wijk KJ, Kessler F (April 2017). "Plastoglobuli: Plastid Microcompartments with Integrated Functions in Metabolism, Plastid Developmental Transitions...
213–219. Archived from the original on 2014-11-07. Saier MH (2013). "Microcompartments and protein machines in prokaryotes". Journal of Molecular Microbiology...
suggests that primitive cells might have formed inside inorganic clay microcompartments, which can provide an ideal container for the synthesis and compartmentalization...
Global Information